Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

L.C. Tsoi; S.L. Spain; J. Knight; E. Ellinghaus; P.E. Stuart; F. Capon; J. Ding; Y. Li; T. Tejasvi; J.E. Gudjonsson; H.M. Kang; M.H. Allen; R. Mcmanus; G. Novelli; L. Samuelsson; J. Schalkwijk; M. Ståhle; A.D. Burden; C.H. Smith; M.J. Cork; X. Estivill; A.M. Bowcock; G.G. Krueger; W. Weger; J. Worthington; R. Tazi-Ahnini; F.O. Nestle; A. Hayday; P. Hoffmann; J. Winkelmann; C. Wijmenga; C. Langford; S. Edkins; R. Andrews; H. Blackburn; A. Strange; G. Band; R.D. Pearson; D. Vukcevic; C.C.A. Spencer; P. Deloukas; U. Mrowietz; S. Schreiber; S. Weidinger; S. Koks; K. Kingo; T. Esko; A. Metspalu; H.W. Lim; J.J. Voorhees; M. Weichenthal; H.E. Wichmann; V. Chandran; C.F. Rosen; P. Rahman; D.D. Gladman; C.E.M. Griffiths; A. Reis; J. Kere; R.P. Nnair; A. Franke; J.N. Barker; G.R. Abecasis; J.T. Eelder; R. Ttrembath; K.C. Duffin; C. Helms; D. Goldgar; J. Paschall; M.J. Malloy; C.R. Pullinger; J.P. Kane; J. Gardner; A. Perlmutter; A. Miner; B.J. Feng; R. Hiremagalore; R.W. Ike; E. Christophers; T. Henseler; A. Ruether; S.J. Schrodi; S. Prahalad; S.L. Guthery; J. Fischer; W. Liao; P. Kwok; A. Menter; G.M. Lathrop; C. Wise; A.B. Begovich; A. Onoufriadis; M.E. Weale; A. Hofer; W. Salmhofer; P. Wolf; K. Kainu; U. Saarialho-Kere; S. Suomela; P. Badorf; U. Hüffmeier; W. Kurrat; W. Küster; J. Lascorz; R. Mössner; F. Schürmeier-Horst; M. Ständer; H. Traupe; J.G.M. Bergboer; M.D. Heijer; P.C. Van De Kerkhof; P.L.J.M. Zeeuwen; L. Barnes; L.E. Campbell; C. Cusack; C. Coleman; J. Conroy; S. Ennis; O. Fitzgerald; P. Gallagher; A.D. Irvine; B. Kirby; T. Markham; W.H.I. Mclean; J. Mcpartlin; S.F. Rogers; A.W. Ryan; A. Zawirska; E. Giardina; T. Lepre; C. Perricone; G. Martín-Ezquerra; R.M. Pujol; E. Riveira-Munoz; A. Inerot; Å.T. Naluai; L. Mallbris; K. Wolk; J. Leman; A. Barton; R.B. Warren; H.S. Young; I. Ricano-Ponce; G. Trynka; F.J. Pellett; A. Henschel; M. Aurand; B. Bebo; C. Gieger; T. Illig; S. Moebus; K.-H. Jöckel; R. Erbel; P. Donnelly; L. Peltonen; Jenefer Blackwell; E. Bramon; M.A. Brown; J.P. Casas; A. Corvin; N. Craddock; A. Duncanson; J. Jankowski; H.S. Markus; C.G. Mathew; M.I. Mccarthy; C.N.A. Palmer; R. Plomin; A. Rautanen; S.J. Sawcer; N. Samani; A.C. Viswanathan; N.W. Wood; C. Bellenguez; C. Freeman; G. Hellenthal; E. Giannoulatou; M. Pirinen; Z. Su; S.E. Hunt; R. Gwilliam; S.J. Bumpstead; S. Dronov; M. Gillman; E. Gray; N. Hammond; A. Jayakumar; O.T. Mccann; J. Liddle; M.L. Perez; S.C. Potter; R. Ravindrarajah; M. Ricketts; M. Waller; P. Weston; S. Widaa; P. Whittaker; R.P. Neir; J.N.W.N. Barker; J.T. Elder; R.C. Trembath

doi:10.1038/ng.2467

Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

L.C. Tsoi, S.L. Spain, J. Knight, E. Ellinghaus, P.E. Stuart, F. Capon, J. Ding, Y. Li, T. Tejasvi, J.E. Gudjonsson, H.M. Kang, M.H. Allen, R. Mcmanus, G. Novelli, L. Samuelsson, J. Schalkwijk, M. Ståhle, A.D. Burden, C.H. Smith, M.J. CorkX. Estivill, A.M. Bowcock, G.G. Krueger, W. Weger, J. Worthington, R. Tazi-Ahnini, F.O. Nestle, A. Hayday, P. Hoffmann, J. Winkelmann, C. Wijmenga, C. Langford, S. Edkins, R. Andrews, H. Blackburn, A. Strange, G. Band, R.D. Pearson, D. Vukcevic, C.C.A. Spencer, P. Deloukas, U. Mrowietz, S. Schreiber, S. Weidinger, S. Koks, K. Kingo, T. Esko, A. Metspalu, H.W. Lim, J.J. Voorhees, M. Weichenthal, H.E. Wichmann, V. Chandran, C.F. Rosen, P. Rahman, D.D. Gladman, C.E.M. Griffiths, A. Reis, J. Kere, R.P. Nnair, A. Franke, J.N. Barker, G.R. Abecasis, J.T. Eelder, R. Ttrembath, K.C. Duffin, C. Helms, D. Goldgar, J. Paschall, M.J. Malloy, C.R. Pullinger, J.P. Kane, J. Gardner, A. Perlmutter, A. Miner, B.J. Feng, R. Hiremagalore, R.W. Ike, E. Christophers, T. Henseler, A. Ruether, S.J. Schrodi, S. Prahalad, S.L. Guthery, J. Fischer, W. Liao, P. Kwok, A. Menter, G.M. Lathrop, C. Wise, A.B. Begovich, A. Onoufriadis, M.E. Weale, A. Hofer, W. Salmhofer, P. Wolf, K. Kainu, U. Saarialho-Kere, S. Suomela, P. Badorf, U. Hüffmeier, W. Kurrat, W. Küster, J. Lascorz, R. Mössner, F. Schürmeier-Horst, M. Ständer, H. Traupe, J.G.M. Bergboer, M.D. Heijer, P.C. Van De Kerkhof, P.L.J.M. Zeeuwen, L. Barnes, L.E. Campbell, C. Cusack, C. Coleman, J. Conroy, S. Ennis, O. Fitzgerald, P. Gallagher, A.D. Irvine, B. Kirby, T. Markham, W.H.I. Mclean, J. Mcpartlin, S.F. Rogers, A.W. Ryan, A. Zawirska, E. Giardina, T. Lepre, C. Perricone, G. Martín-Ezquerra, R.M. Pujol, E. Riveira-Munoz, A. Inerot, Å.T. Naluai, L. Mallbris, K. Wolk, J. Leman, A. Barton, R.B. Warren, H.S. Young, I. Ricano-Ponce, G. Trynka, F.J. Pellett, A. Henschel, M. Aurand, B. Bebo, C. Gieger, T. Illig, S. Moebus, K.-H. Jöckel, R. Erbel, P. Donnelly, L. Peltonen, Jenefer Blackwell, E. Bramon, M.A. Brown, J.P. Casas, A. Corvin, N. Craddock, A. Duncanson, J. Jankowski, H.S. Markus, C.G. Mathew, M.I. Mccarthy, C.N.A. Palmer, R. Plomin, A. Rautanen, S.J. Sawcer, N. Samani, A.C. Viswanathan, N.W. Wood, C. Bellenguez, C. Freeman, G. Hellenthal, E. Giannoulatou, M. Pirinen, Z. Su, S.E. Hunt, R. Gwilliam, S.J. Bumpstead, S. Dronov, M. Gillman, E. Gray, N. Hammond, A. Jayakumar, O.T. Mccann, J. Liddle, M.L. Perez, S.C. Potter, R. Ravindrarajah, M. Ricketts, M. Waller, P. Weston, S. Widaa, P. Whittaker, R.P. Neir, J.N.W.N. Barker, J.T. Elder, R.C. Trembath

UWA Centre for Child Health Research (affiliated with the The Kids Research Institute Australia)

Research output: Contribution to journal › Article › peer-review

829 Citations (Scopus)

Original language	English
Pages (from-to)	1341-1348
Journal	Nature Genetics
Volume	44
Issue number	12
DOIs	https://doi.org/10.1038/ng.2467
Publication status	Published - 2012

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10.1038/ng.2467

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Tsoi, L. C., Spain, S. L., Knight, J., Ellinghaus, E., Stuart, P. E., Capon, F., Ding, J., Li, Y., Tejasvi, T., Gudjonsson, J. E., Kang, H. M., Allen, M. H., Mcmanus, R., Novelli, G., Samuelsson, L., Schalkwijk, J., Ståhle, M., Burden, A. D., Smith, C. H., ... Trembath, R. C. (2012). Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity. Nature Genetics, 44(12), 1341-1348. https://doi.org/10.1038/ng.2467

@article{7132aa575bca41eabe00832003819ba4,

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author = "L.C. Tsoi and S.L. Spain and J. Knight and E. Ellinghaus and P.E. Stuart and F. Capon and J. Ding and Y. Li and T. Tejasvi and J.E. Gudjonsson and H.M. Kang and M.H. Allen and R. Mcmanus and G. Novelli and L. Samuelsson and J. Schalkwijk and M. St{\aa}hle and A.D. Burden and C.H. Smith and M.J. Cork and X. Estivill and A.M. Bowcock and G.G. Krueger and W. Weger and J. Worthington and R. Tazi-Ahnini and F.O. Nestle and A. Hayday and P. Hoffmann and J. Winkelmann and C. Wijmenga and C. Langford and S. Edkins and R. Andrews and H. Blackburn and A. Strange and G. Band and R.D. Pearson and D. Vukcevic and C.C.A. Spencer and P. Deloukas and U. Mrowietz and S. Schreiber and S. Weidinger and S. Koks and K. Kingo and T. Esko and A. Metspalu and H.W. Lim and J.J. Voorhees and M. Weichenthal and H.E. Wichmann and V. Chandran and C.F. Rosen and P. Rahman and D.D. Gladman and C.E.M. Griffiths and A. Reis and J. Kere and R.P. Nnair and A. Franke and J.N. Barker and G.R. Abecasis and J.T. Eelder and R. Ttrembath and K.C. Duffin and C. Helms and D. Goldgar and J. Paschall and M.J. Malloy and C.R. Pullinger and J.P. Kane and J. Gardner and A. Perlmutter and A. Miner and B.J. Feng and R. Hiremagalore and R.W. Ike and E. Christophers and T. Henseler and A. Ruether and S.J. Schrodi and S. Prahalad and S.L. Guthery and J. Fischer and W. Liao and P. Kwok and A. Menter and G.M. Lathrop and C. Wise and A.B. Begovich and A. Onoufriadis and M.E. Weale and A. Hofer and W. Salmhofer and P. Wolf and K. Kainu and U. Saarialho-Kere and S. Suomela and P. Badorf and U. H{\"u}ffmeier and W. Kurrat and W. K{\"u}ster and J. Lascorz and R. M{\"o}ssner and F. Sch{\"u}rmeier-Horst and M. St{\"a}nder and H. Traupe and J.G.M. Bergboer and M.D. Heijer and {Van De Kerkhof}, P.C. and P.L.J.M. Zeeuwen and L. Barnes and L.E. Campbell and C. Cusack and C. Coleman and J. Conroy and S. Ennis and O. Fitzgerald and P. Gallagher and A.D. Irvine and B. Kirby and T. Markham and W.H.I. Mclean and J. Mcpartlin and S.F. Rogers and A.W. Ryan and A. Zawirska and E. Giardina and T. Lepre and C. Perricone and G. Mart{\'i}n-Ezquerra and R.M. Pujol and E. Riveira-Munoz and A. Inerot and {\AA}.T. Naluai and L. Mallbris and K. Wolk and J. Leman and A. Barton and R.B. Warren and H.S. Young and I. Ricano-Ponce and G. Trynka and F.J. Pellett and A. Henschel and M. Aurand and B. Bebo and C. Gieger and T. Illig and S. Moebus and K.-H. J{\"o}ckel and R. Erbel and P. Donnelly and L. Peltonen and Jenefer Blackwell and E. Bramon and M.A. Brown and J.P. Casas and A. Corvin and N. Craddock and A. Duncanson and J. Jankowski and H.S. Markus and C.G. Mathew and M.I. Mccarthy and C.N.A. Palmer and R. Plomin and A. Rautanen and S.J. Sawcer and N. Samani and A.C. Viswanathan and N.W. Wood and C. Bellenguez and C. Freeman and G. Hellenthal and E. Giannoulatou and M. Pirinen and Z. Su and S.E. Hunt and R. Gwilliam and S.J. Bumpstead and S. Dronov and M. Gillman and E. Gray and N. Hammond and A. Jayakumar and O.T. Mccann and J. Liddle and M.L. Perez and S.C. Potter and R. Ravindrarajah and M. Ricketts and M. Waller and P. Weston and S. Widaa and P. Whittaker and R.P. Neir and J.N.W.N. Barker and J.T. Elder and R.C. Trembath",

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doi = "10.1038/ng.2467",

language = "English",

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Tsoi, LC, Spain, SL, Knight, J, Ellinghaus, E, Stuart, PE, Capon, F, Ding, J, Li, Y, Tejasvi, T, Gudjonsson, JE, Kang, HM, Allen, MH, Mcmanus, R, Novelli, G, Samuelsson, L, Schalkwijk, J, Ståhle, M, Burden, AD, Smith, CH, Cork, MJ, Estivill, X, Bowcock, AM, Krueger, GG, Weger, W, Worthington, J, Tazi-Ahnini, R, Nestle, FO, Hayday, A, Hoffmann, P, Winkelmann, J, Wijmenga, C, Langford, C, Edkins, S, Andrews, R, Blackburn, H, Strange, A, Band, G, Pearson, RD, Vukcevic, D, Spencer, CCA, Deloukas, P, Mrowietz, U, Schreiber, S, Weidinger, S, Koks, S, Kingo, K, Esko, T, Metspalu, A, Lim, HW, Voorhees, JJ, Weichenthal, M, Wichmann, HE, Chandran, V, Rosen, CF, Rahman, P, Gladman, DD, Griffiths, CEM, Reis, A, Kere, J, Nnair, RP, Franke, A, Barker, JN, Abecasis, GR, Eelder, JT, Ttrembath, R, Duffin, KC, Helms, C, Goldgar, D, Paschall, J, Malloy, MJ, Pullinger, CR, Kane, JP, Gardner, J, Perlmutter, A, Miner, A, Feng, BJ, Hiremagalore, R, Ike, RW, Christophers, E, Henseler, T, Ruether, A, Schrodi, SJ, Prahalad, S, Guthery, SL, Fischer, J, Liao, W, Kwok, P, Menter, A, Lathrop, GM, Wise, C, Begovich, AB, Onoufriadis, A, Weale, ME, Hofer, A, Salmhofer, W, Wolf, P, Kainu, K, Saarialho-Kere, U, Suomela, S, Badorf, P, Hüffmeier, U, Kurrat, W, Küster, W, Lascorz, J, Mössner, R, Schürmeier-Horst, F, Ständer, M, Traupe, H, Bergboer, JGM, Heijer, MD, Van De Kerkhof, PC, Zeeuwen, PLJM, Barnes, L, Campbell, LE, Cusack, C, Coleman, C, Conroy, J, Ennis, S, Fitzgerald, O, Gallagher, P, Irvine, AD, Kirby, B, Markham, T, Mclean, WHI, Mcpartlin, J, Rogers, SF, Ryan, AW, Zawirska, A, Giardina, E, Lepre, T, Perricone, C, Martín-Ezquerra, G, Pujol, RM, Riveira-Munoz, E, Inerot, A, Naluai, ÅT, Mallbris, L, Wolk, K, Leman, J, Barton, A, Warren, RB, Young, HS, Ricano-Ponce, I, Trynka, G, Pellett, FJ, Henschel, A, Aurand, M, Bebo, B, Gieger, C, Illig, T, Moebus, S, Jöckel, K-H, Erbel, R, Donnelly, P, Peltonen, L, Blackwell, J, Bramon, E, Brown, MA, Casas, JP, Corvin, A, Craddock, N, Duncanson, A, Jankowski, J, Markus, HS, Mathew, CG, Mccarthy, MI, Palmer, CNA, Plomin, R, Rautanen, A, Sawcer, SJ, Samani, N, Viswanathan, AC, Wood, NW, Bellenguez, C, Freeman, C, Hellenthal, G, Giannoulatou, E, Pirinen, M, Su, Z, Hunt, SE, Gwilliam, R, Bumpstead, SJ, Dronov, S, Gillman, M, Gray, E, Hammond, N, Jayakumar, A, Mccann, OT, Liddle, J, Perez, ML, Potter, SC, Ravindrarajah, R, Ricketts, M, Waller, M, Weston, P, Widaa, S, Whittaker, P, Neir, RP, Barker, JNWN, Elder, JT & Trembath, RC 2012, 'Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity', Nature Genetics, vol. 44, no. 12, pp. 1341-1348. https://doi.org/10.1038/ng.2467

TY - JOUR

T1 - Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

AU - Tsoi, L.C.

AU - Spain, S.L.

AU - Knight, J.

AU - Ellinghaus, E.

AU - Stuart, P.E.

AU - Capon, F.

AU - Ding, J.

AU - Li, Y.

AU - Tejasvi, T.

AU - Gudjonsson, J.E.

AU - Kang, H.M.

AU - Allen, M.H.

AU - Mcmanus, R.

AU - Novelli, G.

AU - Samuelsson, L.

AU - Schalkwijk, J.

AU - Ståhle, M.

AU - Burden, A.D.

AU - Smith, C.H.

AU - Cork, M.J.

AU - Estivill, X.

AU - Bowcock, A.M.

AU - Krueger, G.G.

AU - Weger, W.

AU - Worthington, J.

AU - Tazi-Ahnini, R.

AU - Nestle, F.O.

AU - Hayday, A.

AU - Hoffmann, P.

AU - Winkelmann, J.

AU - Wijmenga, C.

AU - Langford, C.

AU - Edkins, S.

AU - Andrews, R.

AU - Blackburn, H.

AU - Strange, A.

AU - Band, G.

AU - Pearson, R.D.

AU - Vukcevic, D.

AU - Spencer, C.C.A.

AU - Deloukas, P.

AU - Mrowietz, U.

AU - Schreiber, S.

AU - Weidinger, S.

AU - Koks, S.

AU - Kingo, K.

AU - Esko, T.

AU - Metspalu, A.

AU - Lim, H.W.

AU - Voorhees, J.J.

AU - Weichenthal, M.

AU - Wichmann, H.E.

AU - Chandran, V.

AU - Rosen, C.F.

AU - Rahman, P.

AU - Gladman, D.D.

AU - Griffiths, C.E.M.

AU - Reis, A.

AU - Kere, J.

AU - Nnair, R.P.

AU - Franke, A.

AU - Barker, J.N.

AU - Abecasis, G.R.

AU - Eelder, J.T.

AU - Ttrembath, R.

AU - Duffin, K.C.

AU - Helms, C.

AU - Goldgar, D.

AU - Paschall, J.

AU - Malloy, M.J.

AU - Pullinger, C.R.

AU - Kane, J.P.

AU - Gardner, J.

AU - Perlmutter, A.

AU - Miner, A.

AU - Feng, B.J.

AU - Hiremagalore, R.

AU - Ike, R.W.

AU - Christophers, E.

AU - Henseler, T.

AU - Ruether, A.

AU - Schrodi, S.J.

AU - Prahalad, S.

AU - Guthery, S.L.

AU - Fischer, J.

AU - Liao, W.

AU - Kwok, P.

AU - Menter, A.

AU - Lathrop, G.M.

AU - Wise, C.

AU - Begovich, A.B.

AU - Onoufriadis, A.

AU - Weale, M.E.

AU - Hofer, A.

AU - Salmhofer, W.

AU - Wolf, P.

AU - Kainu, K.

AU - Saarialho-Kere, U.

AU - Suomela, S.

AU - Badorf, P.

AU - Hüffmeier, U.

AU - Kurrat, W.

AU - Küster, W.

AU - Lascorz, J.

AU - Mössner, R.

AU - Schürmeier-Horst, F.

AU - Ständer, M.

AU - Traupe, H.

AU - Bergboer, J.G.M.

AU - Heijer, M.D.

AU - Van De Kerkhof, P.C.

AU - Zeeuwen, P.L.J.M.

AU - Barnes, L.

AU - Campbell, L.E.

AU - Cusack, C.

AU - Coleman, C.

AU - Conroy, J.

AU - Ennis, S.

AU - Fitzgerald, O.

AU - Gallagher, P.

AU - Irvine, A.D.

AU - Kirby, B.

AU - Markham, T.

AU - Mclean, W.H.I.

AU - Mcpartlin, J.

AU - Rogers, S.F.

AU - Ryan, A.W.

AU - Zawirska, A.

AU - Giardina, E.

AU - Lepre, T.

AU - Perricone, C.

AU - Martín-Ezquerra, G.

AU - Pujol, R.M.

AU - Riveira-Munoz, E.

AU - Inerot, A.

AU - Naluai, Å.T.

AU - Mallbris, L.

AU - Wolk, K.

AU - Leman, J.

AU - Barton, A.

AU - Warren, R.B.

AU - Young, H.S.

AU - Ricano-Ponce, I.

AU - Trynka, G.

AU - Pellett, F.J.

AU - Henschel, A.

AU - Aurand, M.

AU - Bebo, B.

AU - Gieger, C.

AU - Illig, T.

AU - Moebus, S.

AU - Jöckel, K.-H.

AU - Erbel, R.

AU - Donnelly, P.

AU - Peltonen, L.

AU - Blackwell, Jenefer

AU - Bramon, E.

AU - Brown, M.A.

AU - Casas, J.P.

AU - Corvin, A.

AU - Craddock, N.

AU - Duncanson, A.

AU - Jankowski, J.

AU - Markus, H.S.

AU - Mathew, C.G.

AU - Mccarthy, M.I.

AU - Palmer, C.N.A.

AU - Plomin, R.

AU - Rautanen, A.

AU - Sawcer, S.J.

AU - Samani, N.

AU - Viswanathan, A.C.

AU - Wood, N.W.

AU - Bellenguez, C.

AU - Freeman, C.

AU - Hellenthal, G.

AU - Giannoulatou, E.

AU - Pirinen, M.

AU - Su, Z.

AU - Hunt, S.E.

AU - Gwilliam, R.

AU - Bumpstead, S.J.

AU - Dronov, S.

AU - Gillman, M.

AU - Gray, E.

AU - Hammond, N.

AU - Jayakumar, A.

AU - Mccann, O.T.

AU - Liddle, J.

AU - Perez, M.L.

AU - Potter, S.C.

AU - Ravindrarajah, R.

AU - Ricketts, M.

AU - Waller, M.

AU - Weston, P.

AU - Widaa, S.

AU - Whittaker, P.

AU - Neir, R.P.

AU - Barker, J.N.W.N.

AU - Elder, J.T.

AU - Trembath, R.C.

PY - 2012

Y1 - 2012

U2 - 10.1038/ng.2467

DO - 10.1038/ng.2467

M3 - Article

C2 - 23143594

SN - 1061-4036

VL - 44

SP - 1341

EP - 1348

JO - Nature Genetics

JF - Nature Genetics

IS - 12

ER -