Clostridium difficile ribotype 251 strains in Australia

Stacey Hong

Research output: ThesisDoctoral Thesis

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Abstract

Over the last two decades, the epidemiology of Clostridium difficile infection has received significant attention due to the emergence of the epidemic C. difficile PCR ribotype (RT) 027 strain. This strain never established in Australia and there is a different repertoire of circulating C. difficile strains causing human infection. One such strain that has increased in prevalence Australia-wide is RT251. The virulence potential of these strains and the clinical implications were unknown. Thus, the aim of this thesis was to better understand the epidemiology and evolution of C. difficile RT251 strains using complementary epidemiological, genomic and phenotypic approaches.
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • The University of Western Australia
Supervisors/Advisors
  • Riley, Thomas, Supervisor
  • Knight, Dan, Supervisor
  • Chang, Barbara, Supervisor
Thesis sponsors
Award date16 Jul 2021
DOIs
Publication statusUnpublished - 2021

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