Clostridioides (Clostridium) difficile in the home environment in Perth, Western Australia

Niraj Shivaperumal

Research output: ThesisDoctoral Thesis

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Abstract

This research hypothesised that the domestic environment, pets, and food may contribute to the dissemination of Clostridium difficile (CD), leading to CDI in the community. Convenience samples were collected from 23 home gardens, households, and meat samples across various suburbs of Perth, Western Australia. The study unveils a high prevalence of clinically important toxigenic strains with diverse ribotypes and identifies novel strains exclusively producing toxin A. A clinically significant strain, RT002, was detected in cats. Antimicrobial resistance was noted in numerous isolates from various sources. Several novel strains failed to produce black colonies on ChromID agar, exhibiting unique characteristics.
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • The University of Western Australia
Supervisors/Advisors
  • Riley, Thomas, Supervisor
  • Chang, Barbara, Supervisor
Thesis sponsors
Award date16 Apr 2024
DOIs
Publication statusUnpublished - 2023

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