Hyperkalaemia in pigs during anaesthesia for laparoscopic renal transplantation surgery

G. C. Musk, B. He, T. Gaal

Research output: Contribution to journalArticle


This study describes the results of blood samples collected from pigs undergoing lapa- roscopic orthotopic renal transplant. Sixteen Large White pigs and one Duroc pig (mean weight 57kg) underwent anesthesia and surgery. Blood samples were collected immediately after the induction of anaesthesia, at the end of anesthesia, on days 3, 7, 14, 21 and 28 of the
recovery period. Total protein decreased during anaesthesia and the frequency of hyperkalemia at the end of anaesthesia was 0.69. There were no electrocardiographic or haemodynamic disturbances during anaesthesia so the significance of hyperkaleamia in these pigs is unclear.

The potential causes of hyperkalaemia in this context include prolonged recumbency causing muscle damage during surgery, leakage of intra cellular potassium from red blood cells prior to laboratory analysis, compromised renal perfusion, and previously unreported drug effects. Further investigation into the causes and consequences of hyperkalemia in anaesthetized pigs is indicated.
Original languageEnglish
Pages (from-to)273-283
Number of pages9
JournalJournal of Experimental and Applied Animal Sciences
Issue number2
Publication statusPublished - 16 Dec 2014

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