Hyperglycaemic presentations in type 2 diabetes

Research output: Contribution to journalReview article

Abstract

Background
Hyperosmolar hyperglycaemic state (HHS) is a syndrome that occurs in patients with type 2 diabetes mellitus (T2DM) and is comparable to diabetic ketoacidosis (DKA) seen in patients with type 1 diabetes. For a general practitioner working in a rural emergency department, recognition of HHS in a patient presenting with
the triad of severe dehydration, hyperglycaemia and hyperosmolality is important to guide management and plan for disposition.

Objectives
This article reviews the hyperglycaemic states that can occur in patients with T2DM. The reasons for the biochemical derangements in both HHS and DKA are outlined, with a focus on the recognition and management of HHS.

Discussion
Knowledge of the pathophysiology that influences HHS helps understand of
its clinical presentation and treatment. HHS has a high mortality rate (5–20%),
and having access to clinical guidelines from a referring hospital is useful to
guide early management strategies.
Original languageEnglish
Pages (from-to)263
Number of pages267
JournalAustralian journal of general practice
Volume48
Issue number5
Publication statusPublished - May 2019

Fingerprint

Type 2 Diabetes Mellitus
Type 1 Diabetes Mellitus
Dehydration
Hyperglycemia
Inpatients
Guidelines
Mortality
Therapeutics

Cite this

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title = "Hyperglycaemic presentations in type 2 diabetes",
abstract = "BackgroundHyperosmolar hyperglycaemic state (HHS) is a syndrome that occurs in patients with type 2 diabetes mellitus (T2DM) and is comparable to diabetic ketoacidosis (DKA) seen in patients with type 1 diabetes. For a general practitioner working in a rural emergency department, recognition of HHS in a patient presenting withthe triad of severe dehydration, hyperglycaemia and hyperosmolality is important to guide management and plan for disposition.ObjectivesThis article reviews the hyperglycaemic states that can occur in patients with T2DM. The reasons for the biochemical derangements in both HHS and DKA are outlined, with a focus on the recognition and management of HHS.DiscussionKnowledge of the pathophysiology that influences HHS helps understand ofits clinical presentation and treatment. HHS has a high mortality rate (5–20{\%}),and having access to clinical guidelines from a referring hospital is useful toguide early management strategies.",
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Hyperglycaemic presentations in type 2 diabetes. / Griffiths, Emma; Singleton, Sally; Willix, Clare.

In: Australian journal of general practice, Vol. 48, No. 5, 05.2019, p. 263.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Hyperglycaemic presentations in type 2 diabetes

AU - Griffiths, Emma

AU - Singleton, Sally

AU - Willix, Clare

PY - 2019/5

Y1 - 2019/5

N2 - BackgroundHyperosmolar hyperglycaemic state (HHS) is a syndrome that occurs in patients with type 2 diabetes mellitus (T2DM) and is comparable to diabetic ketoacidosis (DKA) seen in patients with type 1 diabetes. For a general practitioner working in a rural emergency department, recognition of HHS in a patient presenting withthe triad of severe dehydration, hyperglycaemia and hyperosmolality is important to guide management and plan for disposition.ObjectivesThis article reviews the hyperglycaemic states that can occur in patients with T2DM. The reasons for the biochemical derangements in both HHS and DKA are outlined, with a focus on the recognition and management of HHS.DiscussionKnowledge of the pathophysiology that influences HHS helps understand ofits clinical presentation and treatment. HHS has a high mortality rate (5–20%),and having access to clinical guidelines from a referring hospital is useful toguide early management strategies.

AB - BackgroundHyperosmolar hyperglycaemic state (HHS) is a syndrome that occurs in patients with type 2 diabetes mellitus (T2DM) and is comparable to diabetic ketoacidosis (DKA) seen in patients with type 1 diabetes. For a general practitioner working in a rural emergency department, recognition of HHS in a patient presenting withthe triad of severe dehydration, hyperglycaemia and hyperosmolality is important to guide management and plan for disposition.ObjectivesThis article reviews the hyperglycaemic states that can occur in patients with T2DM. The reasons for the biochemical derangements in both HHS and DKA are outlined, with a focus on the recognition and management of HHS.DiscussionKnowledge of the pathophysiology that influences HHS helps understand ofits clinical presentation and treatment. HHS has a high mortality rate (5–20%),and having access to clinical guidelines from a referring hospital is useful toguide early management strategies.

UR - https://www1.racgp.org.au/ajgp/home

UR - https://www1.racgp.org.au/ajgp/2019/may/hyperglycaemic-presentations-in-type-2-diabetes

M3 - Review article

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SP - 263

JO - Australian journal of general practice

JF - Australian journal of general practice

SN - 2208-794X

IS - 5

ER -