Horning-Crown Macrocycles: Novel Hybrids of Calixarenes and Crown Ethers

L.T. Higham, U.P. Kreher, Colin Raston, J.L. Scott, C.R. Strauss

Research output: Contribution to journalArticlepeer-review

14 Citations (Scopus)


Novel macrocycles possessing ether linkages and 2,6-disubstituted phenolics were produced in one step and with 100% atom economy by isoaromatization of chameleon macrocyclic precursors possessing 2,6-diarylidenecyclohexanone moieties. Intramolecular hydrogen bonding of the phenolic hydrogen atoms influenced the shape of the macrocycles and dictated host-guest behavior.
Original languageEnglish
Pages (from-to)3261-3264
JournalOrganic Letters
Issue number19
Publication statusPublished - 2004


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