Abstract
This thesis explores the associations of circulating thyroid hormones, sex hormones, and IGF1 and its binding proteins, with cancer incidence in two community-based Australian male cohorts. There was a direct association of serum TSH and IGFBP3 with colorectal cancer risk, and of circulating androgens with lung cancer risk in older men. Increased thyroid hormone exposure was associated with prostate cancer risk in middle-aged men. Hormones did not account for the lower prostate cancer risk in older men with diabetes. Further studies are required to explore the utility of hormones as biomarkers for lung, colorectal and prostate cancer risk in men.
| Original language | English |
|---|---|
| Qualification | Doctor of Philosophy |
| Awarding Institution |
|
| Supervisors/Advisors |
|
| Thesis sponsors | |
| Award date | 30 Dec 2020 |
| DOIs | |
| Publication status | Unpublished - 2020 |
Access to Document
- THESIS - DOCTOR OF PHILOSOPHY - CHAN, Yi Xian - 2020
This work is protected by Copyright. You may print or download ONE copy of this document for the purpose of your own non-commercial research or study. Any other use requires permission from the copyright owner. The Copyright Act requires you to attribute any copyright works you quote or paraphrase.