Histopathology of the Mucosal Potentially Malignant (Dysplastic) Disorders

Muhammed Yakin; Omar Kujan

doi:10.1007/978-3-031-77481-2_29

Histopathology of the Mucosal Potentially Malignant (Dysplastic) Disorders

Muhammed Yakin
, Omar Kujan

Oral Diagnostic and Surgical Sciences

Research output: Chapter in Book/Conference paper › Chapter › peer-review

Abstract

Oral potentially malignant disorders (OPMD) are a group of mucosal disorders characterised by an increased risk of malignant transformation either in the lesion or elsewhere in the clinically normal-appearing mucosa. The most common OPMD include leukoplakia, erythroplakia, proliferative verrucous leukoplakia, lichen planus and related lesions, and actinic cheilitis. The clinical management of this group of diseases varies according to the exact diagnosis. Therefore, risk assessment plays an important role in informing treatment options. The aim of investigations, mainly biopsy, in OPMD is to assess the presence of carcinoma or the presence and degree of oral epithelial dysplasia. This chapter provides an overview of the current classification of OPMD, including the most recent World Health Organization (WHO) classification of head and neck tumours. Also, it details the histopathological features of OPMD in addition to histological features of cellular and architectural of oral epithelial dysplasia.

Original language	English
Title of host publication	Oral Histology and Oral Histopathology
Subtitle of host publication	A Practical Guide for Dental Students and a Companion to Pathologists
Place of Publication	Singapore
Publisher	Springer Science + Business Media
Pages	299-308
Number of pages	10
ISBN (Electronic)	9783031774812
ISBN (Print)	9783031774805
DOIs	https://doi.org/10.1007/978-3-031-77481-2_29
Publication status	Published - 2025

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Access to Document

10.1007/978-3-031-77481-2_29

Cite this

@inbook{ec68a390e65a4e00931f6ae94cb0b44d,

title = "Histopathology of the Mucosal Potentially Malignant (Dysplastic) Disorders",

abstract = "Oral potentially malignant disorders (OPMD) are a group of mucosal disorders characterised by an increased risk of malignant transformation either in the lesion or elsewhere in the clinically normal-appearing mucosa. The most common OPMD include leukoplakia, erythroplakia, proliferative verrucous leukoplakia, lichen planus and related lesions, and actinic cheilitis. The clinical management of this group of diseases varies according to the exact diagnosis. Therefore, risk assessment plays an important role in informing treatment options. The aim of investigations, mainly biopsy, in OPMD is to assess the presence of carcinoma or the presence and degree of oral epithelial dysplasia. This chapter provides an overview of the current classification of OPMD, including the most recent World Health Organization (WHO) classification of head and neck tumours. Also, it details the histopathological features of OPMD in addition to histological features of cellular and architectural of oral epithelial dysplasia.",

keywords = "Epithelial dysplasia, Leukoplakia, Malignant transformation, Oral potentially malignant disorders",

author = "Muhammed Yakin and Omar Kujan",

note = "Publisher Copyright: {\textcopyright} 2025 The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG.",

year = "2025",

doi = "10.1007/978-3-031-77481-2\_29",

language = "English",

isbn = "9783031774805",

pages = "299--308",

booktitle = "Oral Histology and Oral Histopathology",

publisher = "Springer Science + Business Media",

address = "United States",

}

TY - CHAP

T1 - Histopathology of the Mucosal Potentially Malignant (Dysplastic) Disorders

AU - Yakin, Muhammed

AU - Kujan, Omar

PY - 2025

Y1 - 2025

N2 - Oral potentially malignant disorders (OPMD) are a group of mucosal disorders characterised by an increased risk of malignant transformation either in the lesion or elsewhere in the clinically normal-appearing mucosa. The most common OPMD include leukoplakia, erythroplakia, proliferative verrucous leukoplakia, lichen planus and related lesions, and actinic cheilitis. The clinical management of this group of diseases varies according to the exact diagnosis. Therefore, risk assessment plays an important role in informing treatment options. The aim of investigations, mainly biopsy, in OPMD is to assess the presence of carcinoma or the presence and degree of oral epithelial dysplasia. This chapter provides an overview of the current classification of OPMD, including the most recent World Health Organization (WHO) classification of head and neck tumours. Also, it details the histopathological features of OPMD in addition to histological features of cellular and architectural of oral epithelial dysplasia.

AB - Oral potentially malignant disorders (OPMD) are a group of mucosal disorders characterised by an increased risk of malignant transformation either in the lesion or elsewhere in the clinically normal-appearing mucosa. The most common OPMD include leukoplakia, erythroplakia, proliferative verrucous leukoplakia, lichen planus and related lesions, and actinic cheilitis. The clinical management of this group of diseases varies according to the exact diagnosis. Therefore, risk assessment plays an important role in informing treatment options. The aim of investigations, mainly biopsy, in OPMD is to assess the presence of carcinoma or the presence and degree of oral epithelial dysplasia. This chapter provides an overview of the current classification of OPMD, including the most recent World Health Organization (WHO) classification of head and neck tumours. Also, it details the histopathological features of OPMD in addition to histological features of cellular and architectural of oral epithelial dysplasia.

KW - Epithelial dysplasia

KW - Leukoplakia

KW - Malignant transformation

KW - Oral potentially malignant disorders

UR - https://www.scopus.com/pages/publications/105022230529

U2 - 10.1007/978-3-031-77481-2_29

DO - 10.1007/978-3-031-77481-2_29

M3 - Chapter

AN - SCOPUS:105022230529

SN - 9783031774805

SP - 299

EP - 308

BT - Oral Histology and Oral Histopathology

PB - Springer Science + Business Media

CY - Singapore

ER -

Histopathology of the Mucosal Potentially Malignant (Dysplastic) Disorders

Abstract

UN SDGs

Access to Document

Other files and links

Fingerprint

Histopathology of Dental Caries

Histopathology of Non-infective Stomatitis

Histopathology of Salivary Gland Neoplasms

Cite this