High-pressure single-crystal diffraction at the Australian Synchrotron

Stephanie A Boer, Jason R Price, Alan Riboldi-Tunnicliffe, Rachel Williamson, Aston Summers, Gemma F Turner, Isabelle Jones, Charles Bond, Alice Vrielink, Andrew C Marshall, John Hitchings, Stephen A Moggach

Research output: Contribution to journalArticlepeer-review


A new high-pressure single-crystal diffraction setup has been designed and implemented at the Australian Synchrotron for collecting molecular and protein crystal structures. The setup incorporates a modified micro-Merrill-Bassett cell and holder designed specifically to fit onto the horizontal air-bearing goniometer, allowing high-pressure diffraction measurements to be collected with little to no modification of the beamline setup compared with ambient data collections. Compression data for the amino acid, L-threonine, and the protein, hen egg-white lysozyme, were collected, showcasing the capabilities of the setup.

Original languageEnglish
Pages (from-to)841-846
Number of pages6
JournalJournal of Synchrotron Radiation
Issue number4
Publication statusPublished - 15 Jun 2023


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