High correlation of double Debye model parameters in skin cancer detection

Bao C Q Truong, H. D. Tuan, Anthony J. Fitzgerald, Vincent P. Wallace, H. T. Nguyen

    Research output: Chapter in Book/Conference paperConference paper

    8 Citations (Scopus)

    Abstract

    The double Debye model can be used to capture the dielectric response of human skin in terahertz regime due to high water content in the tissue. The increased water proportion is widely considered as a biomarker of carcinogenesis, which gives rise of using this model in skin cancer detection. Therefore, the goal of this paper is to provide a specific analysis of the double Debye parameters in terms of non-melanoma skin cancer classification. Pearson correlation is applied to investigate the sensitivity of these parameters and their combinations to the variation in tumor percentage of skin samples. The most sensitive parameters are then assessed by using the receiver operating characteristic (ROC) plot to confirm their potential of classifying tumor from normal skin. Our positive outcomes support further steps to clinical application of terahertz imaging in skin cancer delineation.

    Original languageEnglish
    Title of host publication2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014
    PublisherIEEE, Institute of Electrical and Electronics Engineers
    Pages718-721
    Number of pages4
    Volume2014
    ISBN (Electronic)9781424479290
    DOIs
    Publication statusPublished - 2 Nov 2014
    Event2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014 - Chicago, United States
    Duration: 26 Aug 201430 Aug 2014

    Conference

    Conference2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014
    CountryUnited States
    CityChicago
    Period26/08/1430/08/14

    Fingerprint

    Skin Neoplasms
    Skin
    Terahertz Imaging
    Water
    ROC Curve
    Tumors
    Neoplasms
    Carcinogenesis
    Biomarkers
    Water content
    Tissue
    Imaging techniques

    Cite this

    Truong, B. C. Q., Tuan, H. D., Fitzgerald, A. J., Wallace, V. P., & Nguyen, H. T. (2014). High correlation of double Debye model parameters in skin cancer detection. In 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014 (Vol. 2014, pp. 718-721). [6943691] IEEE, Institute of Electrical and Electronics Engineers. https://doi.org/10.1109/EMBC.2014.6943691
    Truong, Bao C Q ; Tuan, H. D. ; Fitzgerald, Anthony J. ; Wallace, Vincent P. ; Nguyen, H. T. / High correlation of double Debye model parameters in skin cancer detection. 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014. Vol. 2014 IEEE, Institute of Electrical and Electronics Engineers, 2014. pp. 718-721
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    title = "High correlation of double Debye model parameters in skin cancer detection",
    abstract = "The double Debye model can be used to capture the dielectric response of human skin in terahertz regime due to high water content in the tissue. The increased water proportion is widely considered as a biomarker of carcinogenesis, which gives rise of using this model in skin cancer detection. Therefore, the goal of this paper is to provide a specific analysis of the double Debye parameters in terms of non-melanoma skin cancer classification. Pearson correlation is applied to investigate the sensitivity of these parameters and their combinations to the variation in tumor percentage of skin samples. The most sensitive parameters are then assessed by using the receiver operating characteristic (ROC) plot to confirm their potential of classifying tumor from normal skin. Our positive outcomes support further steps to clinical application of terahertz imaging in skin cancer delineation.",
    author = "Truong, {Bao C Q} and Tuan, {H. D.} and Fitzgerald, {Anthony J.} and Wallace, {Vincent P.} and Nguyen, {H. T.}",
    year = "2014",
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    Truong, BCQ, Tuan, HD, Fitzgerald, AJ, Wallace, VP & Nguyen, HT 2014, High correlation of double Debye model parameters in skin cancer detection. in 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014. vol. 2014, 6943691, IEEE, Institute of Electrical and Electronics Engineers, pp. 718-721, 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014, Chicago, United States, 26/08/14. https://doi.org/10.1109/EMBC.2014.6943691

    High correlation of double Debye model parameters in skin cancer detection. / Truong, Bao C Q; Tuan, H. D.; Fitzgerald, Anthony J.; Wallace, Vincent P.; Nguyen, H. T.

    2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014. Vol. 2014 IEEE, Institute of Electrical and Electronics Engineers, 2014. p. 718-721 6943691.

    Research output: Chapter in Book/Conference paperConference paper

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    T1 - High correlation of double Debye model parameters in skin cancer detection

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    AU - Tuan, H. D.

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    AU - Wallace, Vincent P.

    AU - Nguyen, H. T.

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    AB - The double Debye model can be used to capture the dielectric response of human skin in terahertz regime due to high water content in the tissue. The increased water proportion is widely considered as a biomarker of carcinogenesis, which gives rise of using this model in skin cancer detection. Therefore, the goal of this paper is to provide a specific analysis of the double Debye parameters in terms of non-melanoma skin cancer classification. Pearson correlation is applied to investigate the sensitivity of these parameters and their combinations to the variation in tumor percentage of skin samples. The most sensitive parameters are then assessed by using the receiver operating characteristic (ROC) plot to confirm their potential of classifying tumor from normal skin. Our positive outcomes support further steps to clinical application of terahertz imaging in skin cancer delineation.

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    Truong BCQ, Tuan HD, Fitzgerald AJ, Wallace VP, Nguyen HT. High correlation of double Debye model parameters in skin cancer detection. In 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014. Vol. 2014. IEEE, Institute of Electrical and Electronics Engineers. 2014. p. 718-721. 6943691 https://doi.org/10.1109/EMBC.2014.6943691