High burden of infectious disease and antibiotic use in early life in Australian Aboriginal communities

Will Cuningham, Jodie McVernon, Michael J. Lydeamore, Ross M. Andrews, Jonathan Carapetis, Therese Kearns, Danielle Clucas, Roslyn Gundjirryirr Dhurrkay, Steven Y.C. Tong, Patricia T. Campbell

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Objective: To quantify the childhood infectious disease burden and antibiotic use in the Northern Territory’s East Arnhem region through synthesis and analysis of historical data resources. Methods: We combined primary health clinic data originally reported in three separate publications stemming from the East Arnhem Healthy Skin Project (Jan-01 to Sep-07). Common statistical techniques were used to explore the prevalence of infectious conditions and the seasonality of infections, and to measure rates of antibiotic use. Results: There was a high monthly prevalence of respiratory (mean: 32% [95% confidence interval (CI): 20%, 34%]) and skin (mean: 20% [95%CI: 19%, 22%]) infectious syndromes, with upper respiratory tract infections (mean: 29% [95%CI: 27%, 31%]) and skin sores (mean: 15% [95%CI: 14%, 17%]) the most common conditions. Antibiotics were frequently prescribed with 95% (95%CI: 91%, 97%) of children having received at least one antibiotic prescription by their first birthday, and 47% having received six antibiotic prescriptions; skin sores being a key driver. Conclusions: Early life infections drive high antibiotic prescribing rates in remote Aboriginal communities. Implications for public health: Eliminating skin disease could reduce antibiotic use by almost 20% in children under five years of age in this population.

Original languageEnglish
Pages (from-to)149-155
Number of pages7
JournalAustralian and New Zealand Journal of Public Health
Volume43
Issue number2
DOIs
Publication statusPublished - 1 Apr 2019

Fingerprint

Communicable Diseases
Anti-Bacterial Agents
Confidence Intervals
Skin
Prescriptions
Infection
Skin Diseases
Respiratory Tract Infections
Publications
Public Health
Health
Population

Cite this

Cuningham, Will ; McVernon, Jodie ; Lydeamore, Michael J. ; Andrews, Ross M. ; Carapetis, Jonathan ; Kearns, Therese ; Clucas, Danielle ; Dhurrkay, Roslyn Gundjirryirr ; Tong, Steven Y.C. ; Campbell, Patricia T. / High burden of infectious disease and antibiotic use in early life in Australian Aboriginal communities. In: Australian and New Zealand Journal of Public Health. 2019 ; Vol. 43, No. 2. pp. 149-155.
@article{89f9cb198e504aeca4032f28f93ff8b8,
title = "High burden of infectious disease and antibiotic use in early life in Australian Aboriginal communities",
abstract = "Objective: To quantify the childhood infectious disease burden and antibiotic use in the Northern Territory’s East Arnhem region through synthesis and analysis of historical data resources. Methods: We combined primary health clinic data originally reported in three separate publications stemming from the East Arnhem Healthy Skin Project (Jan-01 to Sep-07). Common statistical techniques were used to explore the prevalence of infectious conditions and the seasonality of infections, and to measure rates of antibiotic use. Results: There was a high monthly prevalence of respiratory (mean: 32{\%} [95{\%} confidence interval (CI): 20{\%}, 34{\%}]) and skin (mean: 20{\%} [95{\%}CI: 19{\%}, 22{\%}]) infectious syndromes, with upper respiratory tract infections (mean: 29{\%} [95{\%}CI: 27{\%}, 31{\%}]) and skin sores (mean: 15{\%} [95{\%}CI: 14{\%}, 17{\%}]) the most common conditions. Antibiotics were frequently prescribed with 95{\%} (95{\%}CI: 91{\%}, 97{\%}) of children having received at least one antibiotic prescription by their first birthday, and 47{\%} having received six antibiotic prescriptions; skin sores being a key driver. Conclusions: Early life infections drive high antibiotic prescribing rates in remote Aboriginal communities. Implications for public health: Eliminating skin disease could reduce antibiotic use by almost 20{\%} in children under five years of age in this population.",
keywords = "antibiotic use, infectious disease, remote Aboriginal communities",
author = "Will Cuningham and Jodie McVernon and Lydeamore, {Michael J.} and Andrews, {Ross M.} and Jonathan Carapetis and Therese Kearns and Danielle Clucas and Dhurrkay, {Roslyn Gundjirryirr} and Tong, {Steven Y.C.} and Campbell, {Patricia T.}",
year = "2019",
month = "4",
day = "1",
doi = "10.1111/1753-6405.12876",
language = "English",
volume = "43",
pages = "149--155",
journal = "Australian & New Zealand Journal of Public Health",
issn = "1326-0200",
publisher = "John Wiley & Sons",
number = "2",

}

Cuningham, W, McVernon, J, Lydeamore, MJ, Andrews, RM, Carapetis, J, Kearns, T, Clucas, D, Dhurrkay, RG, Tong, SYC & Campbell, PT 2019, 'High burden of infectious disease and antibiotic use in early life in Australian Aboriginal communities' Australian and New Zealand Journal of Public Health, vol. 43, no. 2, pp. 149-155. https://doi.org/10.1111/1753-6405.12876

High burden of infectious disease and antibiotic use in early life in Australian Aboriginal communities. / Cuningham, Will; McVernon, Jodie; Lydeamore, Michael J.; Andrews, Ross M.; Carapetis, Jonathan; Kearns, Therese; Clucas, Danielle; Dhurrkay, Roslyn Gundjirryirr; Tong, Steven Y.C.; Campbell, Patricia T.

In: Australian and New Zealand Journal of Public Health, Vol. 43, No. 2, 01.04.2019, p. 149-155.

Research output: Contribution to journalArticle

TY - JOUR

T1 - High burden of infectious disease and antibiotic use in early life in Australian Aboriginal communities

AU - Cuningham, Will

AU - McVernon, Jodie

AU - Lydeamore, Michael J.

AU - Andrews, Ross M.

AU - Carapetis, Jonathan

AU - Kearns, Therese

AU - Clucas, Danielle

AU - Dhurrkay, Roslyn Gundjirryirr

AU - Tong, Steven Y.C.

AU - Campbell, Patricia T.

PY - 2019/4/1

Y1 - 2019/4/1

N2 - Objective: To quantify the childhood infectious disease burden and antibiotic use in the Northern Territory’s East Arnhem region through synthesis and analysis of historical data resources. Methods: We combined primary health clinic data originally reported in three separate publications stemming from the East Arnhem Healthy Skin Project (Jan-01 to Sep-07). Common statistical techniques were used to explore the prevalence of infectious conditions and the seasonality of infections, and to measure rates of antibiotic use. Results: There was a high monthly prevalence of respiratory (mean: 32% [95% confidence interval (CI): 20%, 34%]) and skin (mean: 20% [95%CI: 19%, 22%]) infectious syndromes, with upper respiratory tract infections (mean: 29% [95%CI: 27%, 31%]) and skin sores (mean: 15% [95%CI: 14%, 17%]) the most common conditions. Antibiotics were frequently prescribed with 95% (95%CI: 91%, 97%) of children having received at least one antibiotic prescription by their first birthday, and 47% having received six antibiotic prescriptions; skin sores being a key driver. Conclusions: Early life infections drive high antibiotic prescribing rates in remote Aboriginal communities. Implications for public health: Eliminating skin disease could reduce antibiotic use by almost 20% in children under five years of age in this population.

AB - Objective: To quantify the childhood infectious disease burden and antibiotic use in the Northern Territory’s East Arnhem region through synthesis and analysis of historical data resources. Methods: We combined primary health clinic data originally reported in three separate publications stemming from the East Arnhem Healthy Skin Project (Jan-01 to Sep-07). Common statistical techniques were used to explore the prevalence of infectious conditions and the seasonality of infections, and to measure rates of antibiotic use. Results: There was a high monthly prevalence of respiratory (mean: 32% [95% confidence interval (CI): 20%, 34%]) and skin (mean: 20% [95%CI: 19%, 22%]) infectious syndromes, with upper respiratory tract infections (mean: 29% [95%CI: 27%, 31%]) and skin sores (mean: 15% [95%CI: 14%, 17%]) the most common conditions. Antibiotics were frequently prescribed with 95% (95%CI: 91%, 97%) of children having received at least one antibiotic prescription by their first birthday, and 47% having received six antibiotic prescriptions; skin sores being a key driver. Conclusions: Early life infections drive high antibiotic prescribing rates in remote Aboriginal communities. Implications for public health: Eliminating skin disease could reduce antibiotic use by almost 20% in children under five years of age in this population.

KW - antibiotic use

KW - infectious disease

KW - remote Aboriginal communities

UR - http://www.scopus.com/inward/record.url?scp=85061313873&partnerID=8YFLogxK

U2 - 10.1111/1753-6405.12876

DO - 10.1111/1753-6405.12876

M3 - Article

VL - 43

SP - 149

EP - 155

JO - Australian & New Zealand Journal of Public Health

JF - Australian & New Zealand Journal of Public Health

SN - 1326-0200

IS - 2

ER -