Heterologous synthesis for future green-modular bioindustries: from flavonoids to isoflavonoids

This research actively explores using microbes to manufacture health-promoting compounds for food and medicine. Extracting these compounds from plants is currently a challenge, and genetically modified crops face limitations. The research is focused on isoflavonoids, valuable plant molecules with health benefits. The genes and structure of enzymes involved in isoflavonoid production were studied and the most effective enzymes were identified. The selected enzymes were then used to engineer microbes for isoflavonoid production. Additionally, the enzymes that modify other plant compounds with medicinal potential were also investigated. This work paves the way for innovative methods to produce health-promoting molecules using microbes.