Herpes zoster brachial plexus neuritis

V.A. Fabian, B. Wood, P. Crowley, Byron Kakulas

Research output: Contribution to journalArticlepeer-review

62 Citations (Scopus)

Abstract

This is the first report of brachial plexus inflammation associated with clinical herpes tester paresis. A 78-year-old female with a 3-week history of herpes tester of the C4, C5, and C6 dermatomes developed left upper arm monoplegia. She died from an acute myocardial infarction. Post-mortem provided a rare opportunity to study the neuropathology of herpes tester motor involvement. Histology of the brachial plexus showed extensive lymphocytic infiltration, myelin breakdown, and preservation of axons without vasculitis. The cervical spinal cord showed perivascular lymphocytic cuffing and no anterior horn necrosis. We suggest, the brachial plexus inflammation was a distal extension of a dorsal ganglionitis. Brachial plexus neuritis may be a direct cause of reversible upper limb paresis in herpes tester. We demonstrate the motor neuropathy is an inflammatory demyelinative process consistent with the recovery observed in a number of patients. We postulate post-herpetic neuralgia may be related to an ongoing inflammatory process.
Original languageEnglish
Pages (from-to)61-64
JournalClinical Neuropathology
Volume16
Issue number2
Publication statusPublished - 1997

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