Hereditary Hemochromastosis in the Post-HFE Era

John Olynyk, Debbie Trinder, G.A. Ramm, R.S. Britton, B.R. Bacon

    Research output: Contribution to journalArticlepeer-review

    66 Citations (Scopus)


    Following the discovery of the HFE gene in 1996 and its linkage to the iron overload disorder hereditary hemochromatosis (HH) there have been profound developments in our understanding of the pathogenesis of the biochemical and clinical manifestations of a number of iron overload disorders. This article provides an update of recent developments and key issues relating to iron homeostasis and inherited disorders of iron overload, with emphasis on HFE-related HH, and is based on the content of the American Association for the Study of Liver Diseases Single-Topic Conference entitled “Hemochromatosis: What has Happened After HFE?” which was held at the Emory Convention Center in Atlanta, September 7-9, 2007. (HEPATOLOGY 2008;48:991–1001.)
    Original languageEnglish
    Pages (from-to)991-1001
    Issue number3
    Publication statusPublished - 2008


    Dive into the research topics of 'Hereditary Hemochromastosis in the Post-HFE Era'. Together they form a unique fingerprint.

    Cite this