Hepatitis B/C virus co-infection in Iran: a seroepidemiological study

Shahryar Semnani, Gholamreza Roshandel, Nafiseh Abdolahi, Sima Besharat, Abbas-Ali Keshtkar, Hamidreza Joshaghani, Abdolvahab Moradi, Khodaberdi Kalavi, Ali Jabbari, Mohammad Javad Kabir, Seyed Ahmad Hosseini, Seyed Mehdi Sedaqat, Ahmad Danesh, Danyal Roshandel

Research output: Contribution to journalArticlepeer-review

20 Citations (Scopus)


BACKGROUND/AIMS: As hepatitis B and C virus have the same transmission routes, dual infection may occur. The aim of this study was to determine the seroprevalence of HCV in HBsAg-positive subjects.

METHODS: 139 HBsAg-positive subjects were enrolled in the study. Serum samples were tested using ELISA method for anti-HCV antibodies. Chi-square and Fisher's exact tests were used to compare the proportions.

RESULTS: There were 68 (48.9%) males and 71 (51.1%) females. The mean age was 41.89+/-11.30 years. One case was excluded because of inadequate blood sampling. Anti-HCV antibody was positive in 17 (12.3%) of the 138 remaining subjects. Seropositivity of HCV was similar between female and male patients (p=0.69).

CONCLUSION: The seroprevalence of co-infection with hepatitis B virus and hepatitis C virus in our study was higher than such reports from some countries (Italy), but was in line with worldwide prevalence (>10%).

Original languageEnglish
Pages (from-to)20-1
Number of pages2
JournalTurkish Journal of Gastroenterology
Issue number1
Publication statusPublished - Mar 2007
Externally publishedYes


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