TY - JOUR
T1 - Hepatitis B/C virus co-infection in Iran
T2 - a seroepidemiological study
AU - Semnani, Shahryar
AU - Roshandel, Gholamreza
AU - Abdolahi, Nafiseh
AU - Besharat, Sima
AU - Keshtkar, Abbas-Ali
AU - Joshaghani, Hamidreza
AU - Moradi, Abdolvahab
AU - Kalavi, Khodaberdi
AU - Jabbari, Ali
AU - Kabir, Mohammad Javad
AU - Hosseini, Seyed Ahmad
AU - Sedaqat, Seyed Mehdi
AU - Danesh, Ahmad
AU - Roshandel, Danyal
PY - 2007/3
Y1 - 2007/3
N2 - BACKGROUND/AIMS: As hepatitis B and C virus have the same transmission routes, dual infection may occur. The aim of this study was to determine the seroprevalence of HCV in HBsAg-positive subjects.METHODS: 139 HBsAg-positive subjects were enrolled in the study. Serum samples were tested using ELISA method for anti-HCV antibodies. Chi-square and Fisher's exact tests were used to compare the proportions.RESULTS: There were 68 (48.9%) males and 71 (51.1%) females. The mean age was 41.89+/-11.30 years. One case was excluded because of inadequate blood sampling. Anti-HCV antibody was positive in 17 (12.3%) of the 138 remaining subjects. Seropositivity of HCV was similar between female and male patients (p=0.69).CONCLUSION: The seroprevalence of co-infection with hepatitis B virus and hepatitis C virus in our study was higher than such reports from some countries (Italy), but was in line with worldwide prevalence (>10%).
AB - BACKGROUND/AIMS: As hepatitis B and C virus have the same transmission routes, dual infection may occur. The aim of this study was to determine the seroprevalence of HCV in HBsAg-positive subjects.METHODS: 139 HBsAg-positive subjects were enrolled in the study. Serum samples were tested using ELISA method for anti-HCV antibodies. Chi-square and Fisher's exact tests were used to compare the proportions.RESULTS: There were 68 (48.9%) males and 71 (51.1%) females. The mean age was 41.89+/-11.30 years. One case was excluded because of inadequate blood sampling. Anti-HCV antibody was positive in 17 (12.3%) of the 138 remaining subjects. Seropositivity of HCV was similar between female and male patients (p=0.69).CONCLUSION: The seroprevalence of co-infection with hepatitis B virus and hepatitis C virus in our study was higher than such reports from some countries (Italy), but was in line with worldwide prevalence (>10%).
KW - Adult
KW - Aged
KW - Antibodies, Viral/blood
KW - Enzyme-Linked Immunosorbent Assay
KW - Female
KW - Hepacivirus/immunology
KW - Hepatitis B/epidemiology
KW - Hepatitis B virus/immunology
KW - Hepatitis C/epidemiology
KW - Humans
KW - Iran/epidemiology
KW - Male
KW - Middle Aged
KW - Sampling Studies
KW - Seroepidemiologic Studies
M3 - Article
C2 - 17450490
SN - 1300-4948
VL - 18
SP - 20
EP - 21
JO - Turkish Journal of Gastroenterology
JF - Turkish Journal of Gastroenterology
IS - 1
ER -