Hemoglobin Titusville, a low oxygen affinity variant hemoglobin, in a family of Northern European background

Hong Yuan Luo; Ian Irving; John Prior; Erna Lim; Shawn H. Eung; Timothy P. Skelton; Wendy N. Erber; Martin H. Steinberg; David H.K. Chui

doi:10.1002/ajh.20209

Hemoglobin Titusville, a low oxygen affinity variant hemoglobin, in a family of Northern European background

Hong Yuan Luo, Ian Irving, John Prior, Erna Lim, Shawn H. Eung, Timothy P. Skelton, Wendy N. Erber, Martin H. Steinberg, David H.K. Chui

Research output: Contribution to journal › Article › peer-review

25 Citations (Scopus)

Abstract

We report the second case of Hb Titusville in a family of Northern European background. This variant hemoglobin caused by an α-globln gene mutation has decreased oxygen affinity. Correct diagnosis Is clinically important to spare affected Individuals extensive Investigations Into other causes of low oxygen saturation In peripheral blood.

Original language	English
Pages (from-to)	384-386
Number of pages	3
Journal	American Journal of Hematology
Volume	77
Issue number	4
DOIs	https://doi.org/10.1002/ajh.20209
Publication status	Published - Dec 2004
Externally published	Yes

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title = "Hemoglobin Titusville, a low oxygen affinity variant hemoglobin, in a family of Northern European background",

abstract = "We report the second case of Hb Titusville in a family of Northern European background. This variant hemoglobin caused by an α-globln gene mutation has decreased oxygen affinity. Correct diagnosis Is clinically important to spare affected Individuals extensive Investigations Into other causes of low oxygen saturation In peripheral blood.",

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author = "Luo, {Hong Yuan} and Ian Irving and John Prior and Erna Lim and Eung, {Shawn H.} and Skelton, {Timothy P.} and Erber, {Wendy N.} and Steinberg, {Martin H.} and Chui, {David H.K.}",

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AU - Irving, Ian

AU - Prior, John

AU - Lim, Erna

AU - Eung, Shawn H.

AU - Skelton, Timothy P.

AU - Erber, Wendy N.

AU - Steinberg, Martin H.

AU - Chui, David H.K.

PY - 2004/12

Y1 - 2004/12

N2 - We report the second case of Hb Titusville in a family of Northern European background. This variant hemoglobin caused by an α-globln gene mutation has decreased oxygen affinity. Correct diagnosis Is clinically important to spare affected Individuals extensive Investigations Into other causes of low oxygen saturation In peripheral blood.

AB - We report the second case of Hb Titusville in a family of Northern European background. This variant hemoglobin caused by an α-globln gene mutation has decreased oxygen affinity. Correct diagnosis Is clinically important to spare affected Individuals extensive Investigations Into other causes of low oxygen saturation In peripheral blood.

KW - Hemoglobin Titusville

KW - Low oxygen affinity variant

KW - Northern European background

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M3 - Article

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JO - American Journal of Hematology

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Hemoglobin Titusville, a low oxygen affinity variant hemoglobin, in a family of Northern European background

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