Helicobacter pylori overcomes natural immunity in repeated infections

Björn Stenström, Helen M Windsor, Alma Fulurija, Mohammed Benghezal, M Priyanthi Kumarasinghe, Kazufumi Kimura, Chin Yen Tay, Charlie H Viiala, Hooi C Ee, Wei Lu, Tobias D Schoep, K Mary Webberley, Barry J Marshall

Research output: Contribution to journalArticle

Abstract

Repeated experimental reinfection of two subjects indicates that Helicobacter pylori infection does not promote an immune response protective against future reinfection. Our results highlight the importance of preventing reinfection after eradication, through public health initiatives, and possibly treatment of family members. They indicate difficulties for vaccine development, especially therapeutic vaccines.

Original languageEnglish
Pages (from-to)1026-1033
Number of pages8
JournalClinical Case Reports
Volume4
Issue number11
DOIs
Publication statusPublished - Nov 2016

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  • Cite this

    Stenström, B., Windsor, H. M., Fulurija, A., Benghezal, M., Kumarasinghe, M. P., Kimura, K., Tay, C. Y., Viiala, C. H., Ee, H. C., Lu, W., Schoep, T. D., Webberley, K. M., & Marshall, B. J. (2016). Helicobacter pylori overcomes natural immunity in repeated infections. Clinical Case Reports, 4(11), 1026-1033. https://doi.org/10.1002/ccr3.687