Abstract
[Truncated abstract] INTRODUCTION: Helicobacter pylori is one of the most prevalent infections in the world. Despite this, the health significance in the paediatric population remains less defined and more controversial in comparison to adult infection. Children at high risk of H. pylori infection include those from developing countries, indigenous children and those subjected to socioeconomic deprivation. Many developed countries, including Australia, accept and provide health services for growing numbers of humanitarian refugees arriving from endemic H. pylori regions. AIMS: This thesis aims to investigate active H. pylori infection in African refugee children. Specifically it will define (i) the prevalence and transmission risk factors; (ii) non-invasive diagnostic methods; (iii) the gastrointestinal symptom profile; (iv) the peripheral immune profile and (v) the extra-gastrointestinal manifestations (iron deficiency anaemia (IDA), hepcidin levels and growth restriction) in this cohort. METHODS: A cross-sectional study of refugee children (
| Original language | English |
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| Qualification | Doctor of Philosophy |
| Publication status | Unpublished - 2010 |
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