Helicobacter pylori in Peptic Ulcer Disease

Tadataka Yamada; John G. Searle; Dennis Ahnen; David H. Aipers; Harry B. Greenberg; Martha Gray; Kent B. Joscelyn; Kent B. McNair; Kent B. Jeffrey; Gordon Kauffman; Daniel K. Podolsky; Wayne A. Ray; Dennis Schaberg; Fred E. Silverstein; Michael V. Sivak; Ann L.B. Williams; Robert Yolken; Martin J. Blaser; Geron Borsch; Pelayo Correa; Steven J. Czinn; David Forman; David Y. Graham; Jon L. Isenberg; Dennis M. Jensen; Barry J. Marshall; Julie Parsonnet; Walter L. Peterson; Pentti Sipponen; Duane T. Smoot; Andrew H. Soil; Amnon Sonnenberg; Nicholas J. Talley; W. Grant Thompson; G. N.J. Tytgat; John Walsh; T. Ulf Westblom; Kenneth G. Wormsley; Frank A. Hamilton; Addison B. Scoville; Benjamin T. Burton; Leslie Curtis; Jerry M. Elliott; James Everhart; John H. Ferguson; Willis R. Foster; William H. Hall; Jay H. Hoofnagle; Leslye D. Johnson; John Walsh; Phillip Gorden; Anthony S. Fauci

doi:10.1001/jama.1994.03520010077036

Helicobacter pylori in Peptic Ulcer Disease

Tadataka Yamada, John G. Searle, Dennis Ahnen, David H. Aipers, Harry B. Greenberg, Martha Gray, Kent B. Joscelyn, Kent B. McNair, Kent B. Jeffrey, Gordon Kauffman, Daniel K. Podolsky, Wayne A. Ray, Dennis Schaberg, Fred E. Silverstein, Michael V. Sivak, Ann L.B. Williams, Robert Yolken, Martin J. Blaser, Geron Borsch, Pelayo CorreaSteven J. Czinn, David Forman, David Y. Graham, Jon L. Isenberg, Dennis M. Jensen, Barry J. Marshall, Julie Parsonnet, Walter L. Peterson, Pentti Sipponen, Duane T. Smoot, Andrew H. Soil, Amnon Sonnenberg, Nicholas J. Talley, W. Grant Thompson, G. N.J. Tytgat, John Walsh, T. Ulf Westblom, Kenneth G. Wormsley, Frank A. Hamilton, Addison B. Scoville, Benjamin T. Burton, Leslie Curtis, Jerry M. Elliott, James Everhart, John H. Ferguson, Willis R. Foster, William H. Hall, Jay H. Hoofnagle, Leslye D. Johnson, John Walsh, Phillip Gorden, Anthony S. Fauci

Marshall Centre

Research output: Contribution to journal › Article › peer-review

1527 Citations (Web of Science)

Abstract

The National Institutes of Health Consensus Development Conference on Helicobacter pylori in Peptic Ulcer Disease brought together specialists in gastroenterology, surgery, infectious diseases, epidemiology, and pathology, as well as the public to address the following questions: (1) What is the causal relationship of H pylori to upper gastrointestinal disease? (2) How does one diagnose and eradicate H pylori infection? (3) Does eradication of H pylori infection benefit the patient with peptic ulcer disease? (4) What is the relationship between H pylori infection and gastric malignancy? (5) Which H pylori—infected patients should be treated? (6) What are the most important questions that must be addressed by future research in H pylori infections? Following 1½ days of presentations by experts and discussion by the audience, a consensus panel weighed the evidence and prepared their consensus statement. Among their findings, the consensus panel concluded that (1) ulcer patients with H pylori infection require treatment with antimicrobial agents in addition to antisecretory drugs whether on first presentation with the illness or on recurrence; (2) the value of treating of nonulcerative dyspepsia patients with H pylori infection remains to be determined; and (3) the interesting relationship between H pylori infection and gastric cancers requires further exploration. (JAMA. 1994;272:65-69).

Original language	English
Pages (from-to)	65-69
Number of pages	5
Journal	JAMA: The Journal of the American Medical Association
Volume	272
Issue number	1
DOIs	https://doi.org/10.1001/jama.1994.03520010077036
Publication status	Published - 6 Jul 1994

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1001/jama.1994.03520010077036

Cite this

Yamada, T., Searle, J. G., Ahnen, D., Aipers, D. H., Greenberg, H. B., Gray, M., Joscelyn, K. B., McNair, K. B., Jeffrey, K. B., Kauffman, G., Podolsky, D. K., Ray, W. A., Schaberg, D., Silverstein, F. E., Sivak, M. V., Williams, A. L. B., Yolken, R., Blaser, M. J., Borsch, G., ... Fauci, A. S. (1994). Helicobacter pylori in Peptic Ulcer Disease. JAMA: The Journal of the American Medical Association, 272(1), 65-69. https://doi.org/10.1001/jama.1994.03520010077036

@article{2444a3b187c14645a84f26f800c99074,

title = "Helicobacter pylori in Peptic Ulcer Disease",

abstract = "The National Institutes of Health Consensus Development Conference on Helicobacter pylori in Peptic Ulcer Disease brought together specialists in gastroenterology, surgery, infectious diseases, epidemiology, and pathology, as well as the public to address the following questions: (1) What is the causal relationship of H pylori to upper gastrointestinal disease? (2) How does one diagnose and eradicate H pylori infection? (3) Does eradication of H pylori infection benefit the patient with peptic ulcer disease? (4) What is the relationship between H pylori infection and gastric malignancy? (5) Which H pylori—infected patients should be treated? (6) What are the most important questions that must be addressed by future research in H pylori infections? Following 1½ days of presentations by experts and discussion by the audience, a consensus panel weighed the evidence and prepared their consensus statement. Among their findings, the consensus panel concluded that (1) ulcer patients with H pylori infection require treatment with antimicrobial agents in addition to antisecretory drugs whether on first presentation with the illness or on recurrence; (2) the value of treating of nonulcerative dyspepsia patients with H pylori infection remains to be determined; and (3) the interesting relationship between H pylori infection and gastric cancers requires further exploration. (JAMA. 1994;272:65-69).",

author = "Tadataka Yamada and Searle, {John G.} and Dennis Ahnen and Aipers, {David H.} and Greenberg, {Harry B.} and Martha Gray and Joscelyn, {Kent B.} and McNair, {Kent B.} and Jeffrey, {Kent B.} and Gordon Kauffman and Podolsky, {Daniel K.} and Ray, {Wayne A.} and Dennis Schaberg and Silverstein, {Fred E.} and Sivak, {Michael V.} and Williams, {Ann L.B.} and Robert Yolken and Blaser, {Martin J.} and Geron Borsch and Pelayo Correa and Czinn, {Steven J.} and David Forman and Graham, {David Y.} and Isenberg, {Jon L.} and Jensen, {Dennis M.} and Marshall, {Barry J.} and Julie Parsonnet and Peterson, {Walter L.} and Pentti Sipponen and Smoot, {Duane T.} and Soil, {Andrew H.} and Amnon Sonnenberg and Talley, {Nicholas J.} and Thompson, {W. Grant} and Tytgat, {G. N.J.} and John Walsh and Westblom, {T. Ulf} and Wormsley, {Kenneth G.} and Hamilton, {Frank A.} and Scoville, {Addison B.} and Burton, {Benjamin T.} and Leslie Curtis and Elliott, {Jerry M.} and James Everhart and Ferguson, {John H.} and Foster, {Willis R.} and Hall, {William H.} and Hoofnagle, {Jay H.} and Johnson, {Leslye D.} and John Walsh and Phillip Gorden and Fauci, {Anthony S.}",

year = "1994",

month = jul,

day = "6",

doi = "10.1001/jama.1994.03520010077036",

language = "English",

volume = "272",

pages = "65--69",

journal = "JAMA: The Journal of the American Medical Association",

issn = "0098-7484",

publisher = "American Medical Association",

number = "1",

}

Yamada, T, Searle, JG, Ahnen, D, Aipers, DH, Greenberg, HB, Gray, M, Joscelyn, KB, McNair, KB, Jeffrey, KB, Kauffman, G, Podolsky, DK, Ray, WA, Schaberg, D, Silverstein, FE, Sivak, MV, Williams, ALB, Yolken, R, Blaser, MJ, Borsch, G, Correa, P, Czinn, SJ, Forman, D, Graham, DY, Isenberg, JL, Jensen, DM, Marshall, BJ, Parsonnet, J, Peterson, WL, Sipponen, P, Smoot, DT, Soil, AH, Sonnenberg, A, Talley, NJ, Thompson, WG, Tytgat, GNJ, Walsh, J, Westblom, TU, Wormsley, KG, Hamilton, FA, Scoville, AB, Burton, BT, Curtis, L, Elliott, JM, Everhart, J, Ferguson, JH, Foster, WR, Hall, WH, Hoofnagle, JH, Johnson, LD, Walsh, J, Gorden, P & Fauci, AS 1994, 'Helicobacter pylori in Peptic Ulcer Disease', JAMA: The Journal of the American Medical Association, vol. 272, no. 1, pp. 65-69. https://doi.org/10.1001/jama.1994.03520010077036

TY - JOUR

T1 - Helicobacter pylori in Peptic Ulcer Disease

AU - Yamada, Tadataka

AU - Searle, John G.

AU - Ahnen, Dennis

AU - Aipers, David H.

AU - Greenberg, Harry B.

AU - Gray, Martha

AU - Joscelyn, Kent B.

AU - McNair, Kent B.

AU - Jeffrey, Kent B.

AU - Kauffman, Gordon

AU - Podolsky, Daniel K.

AU - Ray, Wayne A.

AU - Schaberg, Dennis

AU - Silverstein, Fred E.

AU - Sivak, Michael V.

AU - Williams, Ann L.B.

AU - Yolken, Robert

AU - Blaser, Martin J.

AU - Borsch, Geron

AU - Correa, Pelayo

AU - Czinn, Steven J.

AU - Forman, David

AU - Graham, David Y.

AU - Isenberg, Jon L.

AU - Jensen, Dennis M.

AU - Marshall, Barry J.

AU - Parsonnet, Julie

AU - Peterson, Walter L.

AU - Sipponen, Pentti

AU - Smoot, Duane T.

AU - Soil, Andrew H.

AU - Sonnenberg, Amnon

AU - Talley, Nicholas J.

AU - Thompson, W. Grant

AU - Tytgat, G. N.J.

AU - Walsh, John

AU - Westblom, T. Ulf

AU - Wormsley, Kenneth G.

AU - Hamilton, Frank A.

AU - Scoville, Addison B.

AU - Burton, Benjamin T.

AU - Curtis, Leslie

AU - Elliott, Jerry M.

AU - Everhart, James

AU - Ferguson, John H.

AU - Foster, Willis R.

AU - Hall, William H.

AU - Hoofnagle, Jay H.

AU - Johnson, Leslye D.

AU - Walsh, John

AU - Gorden, Phillip

AU - Fauci, Anthony S.

PY - 1994/7/6

Y1 - 1994/7/6

N2 - The National Institutes of Health Consensus Development Conference on Helicobacter pylori in Peptic Ulcer Disease brought together specialists in gastroenterology, surgery, infectious diseases, epidemiology, and pathology, as well as the public to address the following questions: (1) What is the causal relationship of H pylori to upper gastrointestinal disease? (2) How does one diagnose and eradicate H pylori infection? (3) Does eradication of H pylori infection benefit the patient with peptic ulcer disease? (4) What is the relationship between H pylori infection and gastric malignancy? (5) Which H pylori—infected patients should be treated? (6) What are the most important questions that must be addressed by future research in H pylori infections? Following 1½ days of presentations by experts and discussion by the audience, a consensus panel weighed the evidence and prepared their consensus statement. Among their findings, the consensus panel concluded that (1) ulcer patients with H pylori infection require treatment with antimicrobial agents in addition to antisecretory drugs whether on first presentation with the illness or on recurrence; (2) the value of treating of nonulcerative dyspepsia patients with H pylori infection remains to be determined; and (3) the interesting relationship between H pylori infection and gastric cancers requires further exploration. (JAMA. 1994;272:65-69).

AB - The National Institutes of Health Consensus Development Conference on Helicobacter pylori in Peptic Ulcer Disease brought together specialists in gastroenterology, surgery, infectious diseases, epidemiology, and pathology, as well as the public to address the following questions: (1) What is the causal relationship of H pylori to upper gastrointestinal disease? (2) How does one diagnose and eradicate H pylori infection? (3) Does eradication of H pylori infection benefit the patient with peptic ulcer disease? (4) What is the relationship between H pylori infection and gastric malignancy? (5) Which H pylori—infected patients should be treated? (6) What are the most important questions that must be addressed by future research in H pylori infections? Following 1½ days of presentations by experts and discussion by the audience, a consensus panel weighed the evidence and prepared their consensus statement. Among their findings, the consensus panel concluded that (1) ulcer patients with H pylori infection require treatment with antimicrobial agents in addition to antisecretory drugs whether on first presentation with the illness or on recurrence; (2) the value of treating of nonulcerative dyspepsia patients with H pylori infection remains to be determined; and (3) the interesting relationship between H pylori infection and gastric cancers requires further exploration. (JAMA. 1994;272:65-69).

UR - http://www.scopus.com/inward/record.url?scp=0028361702&partnerID=8YFLogxK

U2 - 10.1001/jama.1994.03520010077036

DO - 10.1001/jama.1994.03520010077036

M3 - Article

AN - SCOPUS:0028361702

VL - 272

SP - 65

EP - 69

JO - JAMA: The Journal of the American Medical Association

JF - JAMA: The Journal of the American Medical Association

SN - 0098-7484

IS - 1

ER -

Helicobacter pylori in Peptic Ulcer Disease

Abstract

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this