Abstract
The understanding of cellular gene response to heat therapy has
accelerated with the global epidemic in obesity and diabetes that is
related to chronic diseases such as cardiovascular disease and NAFLD.
Heat therapy that involves Sirt 1 should be carefully assessed with relevance
to Sirt 1’s transcriptional regulation of HSF1/HSP interactions
and with excessive heat therapy may accelerate Sirt 1 mediated HSP
induced cell apoptosis. Heat therapy to maintain glucose homeostasisin diabetic individuals in the developed world may differ from developing
word diabetic individuals that lack the heat shock gene Sirt 1.
Heat therapy intervals that involve sauna versus hot tub temperatures
should be carefully reassessed for safety with relevance to time limits
for heat therapy that may last for weeks/months. Healthy diets that
do not contain saturated fats with heat therapy may prevent global
NAFLD but heat therapy in these individuals may be more successful
with the consumption of Sirt 1 activators versus Sirt 1 inhibitors with
relevance to the reversal of global NAFLD and diabetes.
accelerated with the global epidemic in obesity and diabetes that is
related to chronic diseases such as cardiovascular disease and NAFLD.
Heat therapy that involves Sirt 1 should be carefully assessed with relevance
to Sirt 1’s transcriptional regulation of HSF1/HSP interactions
and with excessive heat therapy may accelerate Sirt 1 mediated HSP
induced cell apoptosis. Heat therapy to maintain glucose homeostasisin diabetic individuals in the developed world may differ from developing
word diabetic individuals that lack the heat shock gene Sirt 1.
Heat therapy intervals that involve sauna versus hot tub temperatures
should be carefully reassessed for safety with relevance to time limits
for heat therapy that may last for weeks/months. Healthy diets that
do not contain saturated fats with heat therapy may prevent global
NAFLD but heat therapy in these individuals may be more successful
with the consumption of Sirt 1 activators versus Sirt 1 inhibitors with
relevance to the reversal of global NAFLD and diabetes.
| Original language | English |
|---|---|
| Pages (from-to) | 1-3 |
| Number of pages | 3 |
| Journal | HSOA Journal of Diabetes and Metabolic Disorders |
| Volume | 4 |
| Issue number | 1 |
| Publication status | Published - 23 Feb 2017 |
