Heat, diet and lifestyles control longevity in animals and man: Atlas of Science. Another view on Science

The inactivation of the heat shock gene called Sirtuin 1 (Sirt 1) is associated with many chronic diseases such as diabetes, non alcoholic fatty liver disease (NAFLD), cardiovascular disease and neurodegenerative diseases. Factors such as body temperature regulation, unhealthy diets and stress can interfere with the heat shock gene and toxic proteins such as heat shock proteins increase and clump with other proteins such as the Alzheimer’s disease amyloid beta. The toxic protein clumps change the body’s immune system and the body attacks itself called autoimmune disease...............................