Harnessing S. cerevisiae to advance the engineering of pentatricopeptide repeat proteins

Farley M. Kwok van der Giezen; Ian Small

doi:10.1111/febs.70438

Harnessing S. cerevisiae to advance the engineering of pentatricopeptide repeat proteins

Research output: Contribution to journal › Comment/debate › peer-review

Abstract

Heterologous expression systems have been instrumental in furthering our understanding of plant RNA editing proteins. In this commentary, we discuss how the establishment of yeast as a model for studying plant RNA editing by Ramanathan et al. could advance the engineering of pentatricopeptide repeat proteins, and how in return pentatricopeptide repeat proteins might be used to advance yeast engineering.

Original language	English
Journal	FEBS Journal
DOIs	https://doi.org/10.1111/febs.70438
Publication status	E-pub ahead of print - 6 Feb 2026

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10.1111/febs.70438Licence: CC BY

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title = "Harnessing S. cerevisiae to advance the engineering of pentatricopeptide repeat proteins",

abstract = "Heterologous expression systems have been instrumental in furthering our understanding of plant RNA editing proteins. In this commentary, we discuss how the establishment of yeast as a model for studying plant RNA editing by Ramanathan et al. could advance the engineering of pentatricopeptide repeat proteins, and how in return pentatricopeptide repeat proteins might be used to advance yeast engineering.",

keywords = "pentatricopeptide repeat protein, Physcomitrium patens, RNA editing, Saccharomyces cerevisiae",

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T1 - Harnessing S. cerevisiae to advance the engineering of pentatricopeptide repeat proteins

AU - Kwok van der Giezen, Farley M.

AU - Small, Ian

PY - 2026/2/6

Y1 - 2026/2/6

N2 - Heterologous expression systems have been instrumental in furthering our understanding of plant RNA editing proteins. In this commentary, we discuss how the establishment of yeast as a model for studying plant RNA editing by Ramanathan et al. could advance the engineering of pentatricopeptide repeat proteins, and how in return pentatricopeptide repeat proteins might be used to advance yeast engineering.

AB - Heterologous expression systems have been instrumental in furthering our understanding of plant RNA editing proteins. In this commentary, we discuss how the establishment of yeast as a model for studying plant RNA editing by Ramanathan et al. could advance the engineering of pentatricopeptide repeat proteins, and how in return pentatricopeptide repeat proteins might be used to advance yeast engineering.

KW - pentatricopeptide repeat protein

KW - Physcomitrium patens

KW - RNA editing

KW - Saccharomyces cerevisiae

UR - https://www.scopus.com/pages/publications/105029462177

U2 - 10.1111/febs.70438

DO - 10.1111/febs.70438

M3 - Comment/debate

C2 - 41645897

AN - SCOPUS:105029462177

SN - 1742-464X

JO - FEBS Journal

JF - FEBS Journal

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Harnessing S. cerevisiae to advance the engineering of pentatricopeptide repeat proteins

Abstract

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