Gonococcal antimicrobial resistance: 80 years in the making

Research output: Contribution to journalArticle

Abstract

Antimicrobial resistance has been a problem for the treatment of gonorrhoea since the introduction of sulfa drugs in the 1930s. The gonococcus has a remarkable ability to obtain the genetic elements required to develop resistance and for these resistant strains to then widely disseminate. Many decades of antibiotic monotherapy have seen the introduction of a number of antibiotic classes herald a promising new era of treatment only to subsequently fail due to resistance development. The world is now faced with the prospect of extensively resistant Neisseria gonorrhoea and requires a coordinated action plan to detect and treat these resistant strains.

Original languageEnglish
Pages (from-to)57-62
Number of pages6
JournalMicrobiology Australia
Volume40
Issue number2
DOIs
Publication statusPublished - May 2019

Cite this

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title = "Gonococcal antimicrobial resistance: 80 years in the making",
abstract = "Antimicrobial resistance has been a problem for the treatment of gonorrhoea since the introduction of sulfa drugs in the 1930s. The gonococcus has a remarkable ability to obtain the genetic elements required to develop resistance and for these resistant strains to then widely disseminate. Many decades of antibiotic monotherapy have seen the introduction of a number of antibiotic classes herald a promising new era of treatment only to subsequently fail due to resistance development. The world is now faced with the prospect of extensively resistant Neisseria gonorrhoea and requires a coordinated action plan to detect and treat these resistant strains.",
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language = "English",
volume = "40",
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journal = "Microbiology Australia",
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Gonococcal antimicrobial resistance : 80 years in the making. / Speers, David.

In: Microbiology Australia, Vol. 40, No. 2, 05.2019, p. 57-62.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Gonococcal antimicrobial resistance

T2 - 80 years in the making

AU - Speers, David

PY - 2019/5

Y1 - 2019/5

N2 - Antimicrobial resistance has been a problem for the treatment of gonorrhoea since the introduction of sulfa drugs in the 1930s. The gonococcus has a remarkable ability to obtain the genetic elements required to develop resistance and for these resistant strains to then widely disseminate. Many decades of antibiotic monotherapy have seen the introduction of a number of antibiotic classes herald a promising new era of treatment only to subsequently fail due to resistance development. The world is now faced with the prospect of extensively resistant Neisseria gonorrhoea and requires a coordinated action plan to detect and treat these resistant strains.

AB - Antimicrobial resistance has been a problem for the treatment of gonorrhoea since the introduction of sulfa drugs in the 1930s. The gonococcus has a remarkable ability to obtain the genetic elements required to develop resistance and for these resistant strains to then widely disseminate. Many decades of antibiotic monotherapy have seen the introduction of a number of antibiotic classes herald a promising new era of treatment only to subsequently fail due to resistance development. The world is now faced with the prospect of extensively resistant Neisseria gonorrhoea and requires a coordinated action plan to detect and treat these resistant strains.

KW - NEISSERIA-GONORRHOEAE

KW - UNCOMPLICATED GONORRHEA

KW - CEFTRIAXONE

KW - AZITHROMYCIN

KW - ADULTS

KW - STRAIN

KW - ERA

U2 - 10.1071/MA19017

DO - 10.1071/MA19017

M3 - Article

VL - 40

SP - 57

EP - 62

JO - Microbiology Australia

JF - Microbiology Australia

SN - 1324-4272

IS - 2

ER -