Glycemia, Treatment Satisfaction, Cognition, and Sleep Quality in Adults and Adolescents with Type 1 Diabetes When Using a Closed-Loop System Overnight Versus Sensor-Augmented Pump with Low-Glucose Suspend Function: A Randomized Crossover Study

A. Sharifi, Martin de Bock, D. Jayawardene, M.M. M. Loh, J.C. C. Horsburgh, C.L. L. Berthold, N. Paramalingam, L.A. A. Bach, P.G. G. Colman, Elizabeth A. Davis, B. Grosman, C. Hendrieckx, A.J. J. Jenkins, K. Kumareswaran, N. Kurtz, A. Kyoong, R.J. J. MacIsaac, J. Speight, S. Trawley, G.M. M. WardA. Roy, Timothy W. Jones, D.N. N. O'Neal

    Research output: Contribution to journalArticle

    43 Citations (Scopus)

    Abstract

    © 2016, Mary Ann Liebert, Inc.Background: We compared glycemia, treatment satisfaction, sleep quality, and cognition using a nighttime Android-based hybrid closed-loop system (Android-HCLS) with sensor-augmented pump with low-glucose suspend function (SAP-LGS) in people with type 1 diabetes. Materials and Methods: An open-label, prospective, randomized crossover study of 16 adults (mean [SD] age 42.1 [9.6] years) and 12 adolescents (15.2 [1.6] years) was conducted. All participants completed four consecutive nights at home with Android-HCLS (proportional integral derivative with insulin feedback algorithm; Medtronic) and SAP-LGS. Primary outcome: percent continuous glucose monitoring (CGM) time (00:00-08:00 h) within target range (72-144 mg/dL). Secondary endpoints: percent CGM time above target (>144 mg/dL); below target (
    Original languageEnglish
    Pages (from-to)772-783
    Number of pages12
    JournalDiabetes Technology and Therapeutics
    Volume18
    Issue number12
    DOIs
    Publication statusPublished - 2016

    Fingerprint Dive into the research topics of 'Glycemia, Treatment Satisfaction, Cognition, and Sleep Quality in Adults and Adolescents with Type 1 Diabetes When Using a Closed-Loop System Overnight Versus Sensor-Augmented Pump with Low-Glucose Suspend Function: A Randomized Crossover Study'. Together they form a unique fingerprint.

  • Cite this

    Sharifi, A., de Bock, M., Jayawardene, D., Loh, M. M. M., Horsburgh, J. C. C., Berthold, C. L. L., Paramalingam, N., Bach, L. A. A., Colman, P. G. G., Davis, E. A., Grosman, B., Hendrieckx, C., Jenkins, A. J. J., Kumareswaran, K., Kurtz, N., Kyoong, A., MacIsaac, R. J. J., Speight, J., Trawley, S., ... O'Neal, D. N. N. (2016). Glycemia, Treatment Satisfaction, Cognition, and Sleep Quality in Adults and Adolescents with Type 1 Diabetes When Using a Closed-Loop System Overnight Versus Sensor-Augmented Pump with Low-Glucose Suspend Function: A Randomized Crossover Study. Diabetes Technology and Therapeutics, 18(12), 772-783. https://doi.org/10.1089/dia.2016.0288