Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function

M.S. Artigas; D.W. Loth; L.V. Wain; S.A. Gharib; M. Obeidat; W. Tang; G. Zhai; J.H. Zhao; A.V. Smith; J.E. Huffman; E. Albrecht; C.M. Jackson; D.M. Evans; Gemma Cadby; M. Fornage; A. Manichaikul; L.M. Lopez; T. Johnson; M.C. Aldrich; T. Aspelund; I. Barroso; H. Campbell; P.A. Cassano; D.J. Couper; G. Eiriksdottir; N. Franceschini; M. Garcia; C. Gieger; G.K. Gislason; I. Grkovic; C.J. Hammond; D.B. Hancock; T.B. Harris; A. Ramasamy; S.R. Heckbert; M. Heliövaara; G. Homuth; P.G. Hysi; Alan James; S. Jankovic; B.R. Joubert; S. Karrasch; N. Klopp; B. Koch; S.B. Kritchevsky; L.J. Launer; Y. Liu; L.R. Loehr; K. Lohman; R.J.F. Loos; T. Lumley; K.A. Al Balushi; Wei Ang; R.G. Barr; John Beilby; J.D. Blakey; M. Boban; V. Boraska; J. Brisman; J.R. Britton; G.G. Brusselle; C. Cooper; I. Curjuric; S. Dahgam; I.J. Deary; S. Ebrahim; M. Eijgelsheim; C. Francks; D. Gaysina; R. Granell; X. Gu; J.L. Hankinson; R. Hardy; S.E. Harris; J. Henderson; A. Henry; A.D. Hingorani; A. Hofman; Patrick Holt; Jennie Hui; Michael Hunter; M. Imboden; K.A. Jameson; S.M. Kerr; I. Kolcic; F. Kronenberg; J.Z. Liu; J. Marchini; T. Mckeever; A.D. Morris; A.-C. Olin; D.J. Porteous; D.S. Postma; S.S. Rich; S.M. Ring; F. Rivadeneira; T. Rochat; A.A. Sayer; I. Sayers; Peter Sly; G.D. Smith; A. Sood; J.M. Starr; A.G. Uitterlinden; J.M. Vonk; S.G. Wannamethee; P.H. Whincup; C. Wijmenga; O.D. Williams; A. Wong; M. Mangino; K.D. Marciante; W.L. Mcardle; B. Meibohm; A.C. Morrison; K.E. North; E. Omenaas; L.J. Palmer; K.H. Pietiläinen; I. Pin; O. Polašek; A. Pouta; B.M. Psaty; A.-L. Hartikainen; T. Rantanen; S. Ripatti; J.I. Rotter; I. Rudan; A.R. Rudnicka; H. Schulz; S.-Y. Shin; T.D. Spector; I. Surakka; V. Vitart; H. Völzke; N.J. Wareham; Nicole Warrington; H.-E. Wichmann; S.H. Wild; J.B. Wilk; M. Wjst; A.F. Wright; L. Zgaga; T. Zemunik; Craig Pennell; F. Nyberg; D. Kuh; J.W. Holloway; H.M. Boezen; D.A. Lawlor; R.W. Morris; N. Probst-Hensch; J. Kaprio; J.F. Wilson; C. Hayward; M. Kähönen; J. Heinrich; Arthur Musk; D.L. Jarvis; S. Gläser; M.-R. Järvelin; B.H. Ch Stricker; P. Elliott; G.T. O'Connor; D.P. Strachan; S.J. London; I.P. Hall; V. Gudnason; M.D. Tobin

doi:10.1038/ng.941

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function

M.S. Artigas, D.W. Loth, L.V. Wain, S.A. Gharib, M. Obeidat, W. Tang, G. Zhai, J.H. Zhao, A.V. Smith, J.E. Huffman, E. Albrecht, C.M. Jackson, D.M. Evans, Gemma Cadby, M. Fornage, A. Manichaikul, L.M. Lopez, T. Johnson, M.C. Aldrich, T. AspelundI. Barroso, H. Campbell, P.A. Cassano, D.J. Couper, G. Eiriksdottir, N. Franceschini, M. Garcia, C. Gieger, G.K. Gislason, I. Grkovic, C.J. Hammond, D.B. Hancock, T.B. Harris, A. Ramasamy, S.R. Heckbert, M. Heliövaara, G. Homuth, P.G. Hysi, Alan James, S. Jankovic, B.R. Joubert, S. Karrasch, N. Klopp, B. Koch, S.B. Kritchevsky, L.J. Launer, Y. Liu, L.R. Loehr, K. Lohman, R.J.F. Loos, T. Lumley, K.A. Al Balushi, Wei Ang, R.G. Barr, John Beilby, J.D. Blakey, M. Boban, V. Boraska, J. Brisman, J.R. Britton, G.G. Brusselle, C. Cooper, I. Curjuric, S. Dahgam, I.J. Deary, S. Ebrahim, M. Eijgelsheim, C. Francks, D. Gaysina, R. Granell, X. Gu, J.L. Hankinson, R. Hardy, S.E. Harris, J. Henderson, A. Henry, A.D. Hingorani, A. Hofman, Patrick Holt, Jennie Hui, Michael Hunter, M. Imboden, K.A. Jameson, S.M. Kerr, I. Kolcic, F. Kronenberg, J.Z. Liu, J. Marchini, T. Mckeever, A.D. Morris, A.-C. Olin, D.J. Porteous, D.S. Postma, S.S. Rich, S.M. Ring, F. Rivadeneira, T. Rochat, A.A. Sayer, I. Sayers, Peter Sly, G.D. Smith, A. Sood, J.M. Starr, A.G. Uitterlinden, J.M. Vonk, S.G. Wannamethee, P.H. Whincup, C. Wijmenga, O.D. Williams, A. Wong, M. Mangino, K.D. Marciante, W.L. Mcardle, B. Meibohm, A.C. Morrison, K.E. North, E. Omenaas, L.J. Palmer, K.H. Pietiläinen, I. Pin, O. Polašek, A. Pouta, B.M. Psaty, A.-L. Hartikainen, T. Rantanen, S. Ripatti, J.I. Rotter, I. Rudan, A.R. Rudnicka, H. Schulz, S.-Y. Shin, T.D. Spector, I. Surakka, V. Vitart, H. Völzke, N.J. Wareham, Nicole Warrington, H.-E. Wichmann, S.H. Wild, J.B. Wilk, M. Wjst, A.F. Wright, L. Zgaga, T. Zemunik, Craig Pennell, F. Nyberg, D. Kuh, J.W. Holloway, H.M. Boezen, D.A. Lawlor, R.W. Morris, N. Probst-Hensch, J. Kaprio, J.F. Wilson, C. Hayward, M. Kähönen, J. Heinrich, Arthur Musk, D.L. Jarvis, S. Gläser, M.-R. Järvelin, B.H. Ch Stricker, P. Elliott, G.T. O'Connor, D.P. Strachan, S.J. London, I.P. Hall, V. Gudnason, M.D. Tobin

Research output: Contribution to journal › Article › peer-review

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Original language	English
Pages (from-to)	1082-1090
Journal	Nature Genetics
Volume	43
Issue number	11
DOIs	https://doi.org/10.1038/ng.941
Publication status	Published - 2011

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Cite this

Artigas, M. S., Loth, D. W., Wain, L. V., Gharib, S. A., Obeidat, M., Tang, W., Zhai, G., Zhao, J. H., Smith, A. V., Huffman, J. E., Albrecht, E., Jackson, C. M., Evans, D. M., Cadby, G., Fornage, M., Manichaikul, A., Lopez, L. M., Johnson, T., Aldrich, M. C., ... Tobin, M. D. (2011). Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. Nature Genetics, 43(11), 1082-1090. https://doi.org/10.1038/ng.941

@article{c02ea060eaa1429995d338395d949194,

title = "Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function",

author = "M.S. Artigas and D.W. Loth and L.V. Wain and S.A. Gharib and M. Obeidat and W. Tang and G. Zhai and J.H. Zhao and A.V. Smith and J.E. Huffman and E. Albrecht and C.M. Jackson and D.M. Evans and Gemma Cadby and M. Fornage and A. Manichaikul and L.M. Lopez and T. Johnson and M.C. Aldrich and T. Aspelund and I. Barroso and H. Campbell and P.A. Cassano and D.J. Couper and G. Eiriksdottir and N. Franceschini and M. Garcia and C. Gieger and G.K. Gislason and I. Grkovic and C.J. Hammond and D.B. Hancock and T.B. Harris and A. Ramasamy and S.R. Heckbert and M. Heli{\"o}vaara and G. Homuth and P.G. Hysi and Alan James and S. Jankovic and B.R. Joubert and S. Karrasch and N. Klopp and B. Koch and S.B. Kritchevsky and L.J. Launer and Y. Liu and L.R. Loehr and K. Lohman and R.J.F. Loos and T. Lumley and {Al Balushi}, K.A. and Wei Ang and R.G. Barr and John Beilby and J.D. Blakey and M. Boban and V. Boraska and J. Brisman and J.R. Britton and G.G. Brusselle and C. Cooper and I. Curjuric and S. Dahgam and I.J. Deary and S. Ebrahim and M. Eijgelsheim and C. Francks and D. Gaysina and R. Granell and X. Gu and J.L. Hankinson and R. Hardy and S.E. Harris and J. Henderson and A. Henry and A.D. Hingorani and A. Hofman and Patrick Holt and Jennie Hui and Michael Hunter and M. Imboden and K.A. Jameson and S.M. Kerr and I. Kolcic and F. Kronenberg and J.Z. Liu and J. Marchini and T. Mckeever and A.D. Morris and A.-C. Olin and D.J. Porteous and D.S. Postma and S.S. Rich and S.M. Ring and F. Rivadeneira and T. Rochat and A.A. Sayer and I. Sayers and Peter Sly and G.D. Smith and A. Sood and J.M. Starr and A.G. Uitterlinden and J.M. Vonk and S.G. Wannamethee and P.H. Whincup and C. Wijmenga and O.D. Williams and A. Wong and M. Mangino and K.D. Marciante and W.L. Mcardle and B. Meibohm and A.C. Morrison and K.E. North and E. Omenaas and L.J. Palmer and K.H. Pietil{\"a}inen and I. Pin and O. Pola{\v s}ek and A. Pouta and B.M. Psaty and A.-L. Hartikainen and T. Rantanen and S. Ripatti and J.I. Rotter and I. Rudan and A.R. Rudnicka and H. Schulz and S.-Y. Shin and T.D. Spector and I. Surakka and V. Vitart and H. V{\"o}lzke and N.J. Wareham and Nicole Warrington and H.-E. Wichmann and S.H. Wild and J.B. Wilk and M. Wjst and A.F. Wright and L. Zgaga and T. Zemunik and Craig Pennell and F. Nyberg and D. Kuh and J.W. Holloway and H.M. Boezen and D.A. Lawlor and R.W. Morris and N. Probst-Hensch and J. Kaprio and J.F. Wilson and C. Hayward and M. K{\"a}h{\"o}nen and J. Heinrich and Arthur Musk and D.L. Jarvis and S. Gl{\"a}ser and M.-R. J{\"a}rvelin and {Ch Stricker}, B.H. and P. Elliott and G.T. O'Connor and D.P. Strachan and S.J. London and I.P. Hall and V. Gudnason and M.D. Tobin",

year = "2011",

doi = "10.1038/ng.941",

language = "English",

volume = "43",

pages = "1082--1090",

journal = "Nature Genetics",

issn = "1061-4036",

publisher = "Nature Publishing Group - Macmillan Publishers",

number = "11",

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Artigas, MS, Loth, DW, Wain, LV, Gharib, SA, Obeidat, M, Tang, W, Zhai, G, Zhao, JH, Smith, AV, Huffman, JE, Albrecht, E, Jackson, CM, Evans, DM, Cadby, G, Fornage, M, Manichaikul, A, Lopez, LM, Johnson, T, Aldrich, MC, Aspelund, T, Barroso, I, Campbell, H, Cassano, PA, Couper, DJ, Eiriksdottir, G, Franceschini, N, Garcia, M, Gieger, C, Gislason, GK, Grkovic, I, Hammond, CJ, Hancock, DB, Harris, TB, Ramasamy, A, Heckbert, SR, Heliövaara, M, Homuth, G, Hysi, PG, James, A, Jankovic, S, Joubert, BR, Karrasch, S, Klopp, N, Koch, B, Kritchevsky, SB, Launer, LJ, Liu, Y, Loehr, LR, Lohman, K, Loos, RJF, Lumley, T, Al Balushi, KA, Ang, W, Barr, RG, Beilby, J , Blakey, JD, Boban, M, Boraska, V, Brisman, J, Britton, JR, Brusselle, GG, Cooper, C, Curjuric, I, Dahgam, S, Deary, IJ, Ebrahim, S, Eijgelsheim, M, Francks, C, Gaysina, D, Granell, R, Gu, X, Hankinson, JL, Hardy, R, Harris, SE, Henderson, J, Henry, A, Hingorani, AD, Hofman, A, Holt, P , Hui, J , Hunter, M, Imboden, M, Jameson, KA, Kerr, SM, Kolcic, I, Kronenberg, F, Liu, JZ, Marchini, J, Mckeever, T, Morris, AD, Olin, A-C, Porteous, DJ, Postma, DS, Rich, SS, Ring, SM, Rivadeneira, F, Rochat, T, Sayer, AA, Sayers, I, Sly, P, Smith, GD, Sood, A, Starr, JM, Uitterlinden, AG, Vonk, JM, Wannamethee, SG, Whincup, PH, Wijmenga, C, Williams, OD, Wong, A, Mangino, M, Marciante, KD, Mcardle, WL, Meibohm, B, Morrison, AC, North, KE, Omenaas, E, Palmer, LJ, Pietiläinen, KH, Pin, I, Polašek, O, Pouta, A, Psaty, BM, Hartikainen, A-L, Rantanen, T, Ripatti, S, Rotter, JI, Rudan, I, Rudnicka, AR, Schulz, H, Shin, S-Y, Spector, TD, Surakka, I, Vitart, V, Völzke, H, Wareham, NJ, Warrington, N, Wichmann, H-E, Wild, SH, Wilk, JB, Wjst, M, Wright, AF, Zgaga, L, Zemunik, T, Pennell, C, Nyberg, F, Kuh, D, Holloway, JW, Boezen, HM, Lawlor, DA, Morris, RW, Probst-Hensch, N, Kaprio, J, Wilson, JF, Hayward, C, Kähönen, M, Heinrich, J, Musk, A, Jarvis, DL, Gläser, S, Järvelin, M-R, Ch Stricker, BH, Elliott, P, O'Connor, GT, Strachan, DP, London, SJ, Hall, IP, Gudnason, V & Tobin, MD 2011, 'Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function', Nature Genetics, vol. 43, no. 11, pp. 1082-1090. https://doi.org/10.1038/ng.941

TY - JOUR

T1 - Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function

AU - Artigas, M.S.

AU - Loth, D.W.

AU - Wain, L.V.

AU - Gharib, S.A.

AU - Obeidat, M.

AU - Tang, W.

AU - Zhai, G.

AU - Zhao, J.H.

AU - Smith, A.V.

AU - Huffman, J.E.

AU - Albrecht, E.

AU - Jackson, C.M.

AU - Evans, D.M.

AU - Cadby, Gemma

AU - Fornage, M.

AU - Manichaikul, A.

AU - Lopez, L.M.

AU - Johnson, T.

AU - Aldrich, M.C.

AU - Aspelund, T.

AU - Barroso, I.

AU - Campbell, H.

AU - Cassano, P.A.

AU - Couper, D.J.

AU - Eiriksdottir, G.

AU - Franceschini, N.

AU - Garcia, M.

AU - Gieger, C.

AU - Gislason, G.K.

AU - Grkovic, I.

AU - Hammond, C.J.

AU - Hancock, D.B.

AU - Harris, T.B.

AU - Ramasamy, A.

AU - Heckbert, S.R.

AU - Heliövaara, M.

AU - Homuth, G.

AU - Hysi, P.G.

AU - James, Alan

AU - Jankovic, S.

AU - Joubert, B.R.

AU - Karrasch, S.

AU - Klopp, N.

AU - Koch, B.

AU - Kritchevsky, S.B.

AU - Launer, L.J.

AU - Liu, Y.

AU - Loehr, L.R.

AU - Lohman, K.

AU - Loos, R.J.F.

AU - Lumley, T.

AU - Al Balushi, K.A.

AU - Ang, Wei

AU - Barr, R.G.

AU - Beilby, John

AU - Blakey, J.D.

AU - Boban, M.

AU - Boraska, V.

AU - Brisman, J.

AU - Britton, J.R.

AU - Brusselle, G.G.

AU - Cooper, C.

AU - Curjuric, I.

AU - Dahgam, S.

AU - Deary, I.J.

AU - Ebrahim, S.

AU - Eijgelsheim, M.

AU - Francks, C.

AU - Gaysina, D.

AU - Granell, R.

AU - Gu, X.

AU - Hankinson, J.L.

AU - Hardy, R.

AU - Harris, S.E.

AU - Henderson, J.

AU - Henry, A.

AU - Hingorani, A.D.

AU - Hofman, A.

AU - Holt, Patrick

AU - Hui, Jennie

AU - Hunter, Michael

AU - Imboden, M.

AU - Jameson, K.A.

AU - Kerr, S.M.

AU - Kolcic, I.

AU - Kronenberg, F.

AU - Liu, J.Z.

AU - Marchini, J.

AU - Mckeever, T.

AU - Morris, A.D.

AU - Olin, A.-C.

AU - Porteous, D.J.

AU - Postma, D.S.

AU - Rich, S.S.

AU - Ring, S.M.

AU - Rivadeneira, F.

AU - Rochat, T.

AU - Sayer, A.A.

AU - Sayers, I.

AU - Sly, Peter

AU - Smith, G.D.

AU - Sood, A.

AU - Starr, J.M.

AU - Uitterlinden, A.G.

AU - Vonk, J.M.

AU - Wannamethee, S.G.

AU - Whincup, P.H.

AU - Wijmenga, C.

AU - Williams, O.D.

AU - Wong, A.

AU - Mangino, M.

AU - Marciante, K.D.

AU - Mcardle, W.L.

AU - Meibohm, B.

AU - Morrison, A.C.

AU - North, K.E.

AU - Omenaas, E.

AU - Palmer, L.J.

AU - Pietiläinen, K.H.

AU - Pin, I.

AU - Polašek, O.

AU - Pouta, A.

AU - Psaty, B.M.

AU - Hartikainen, A.-L.

AU - Rantanen, T.

AU - Ripatti, S.

AU - Rotter, J.I.

AU - Rudan, I.

AU - Rudnicka, A.R.

AU - Schulz, H.

AU - Shin, S.-Y.

AU - Spector, T.D.

AU - Surakka, I.

AU - Vitart, V.

AU - Völzke, H.

AU - Wareham, N.J.

AU - Warrington, Nicole

AU - Wichmann, H.-E.

AU - Wild, S.H.

AU - Wilk, J.B.

AU - Wjst, M.

AU - Wright, A.F.

AU - Zgaga, L.

AU - Zemunik, T.

AU - Pennell, Craig

AU - Nyberg, F.

AU - Kuh, D.

AU - Holloway, J.W.

AU - Boezen, H.M.

AU - Lawlor, D.A.

AU - Morris, R.W.

AU - Probst-Hensch, N.

AU - Kaprio, J.

AU - Wilson, J.F.

AU - Hayward, C.

AU - Kähönen, M.

AU - Heinrich, J.

AU - Musk, Arthur

AU - Jarvis, D.L.

AU - Gläser, S.

AU - Järvelin, M.-R.

AU - Ch Stricker, B.H.

AU - Elliott, P.

AU - O'Connor, G.T.

AU - Strachan, D.P.

AU - London, S.J.

AU - Hall, I.P.

AU - Gudnason, V.

AU - Tobin, M.D.

PY - 2011

Y1 - 2011

U2 - 10.1038/ng.941

DO - 10.1038/ng.941

M3 - Article

C2 - 21946350

SN - 1061-4036

VL - 43

SP - 1082

EP - 1090

JO - Nature Genetics

JF - Nature Genetics

IS - 11

ER -