Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus

Y. Lu; V. Vitart; K.P. Burdon; C.C. Khor; Y. Bykhovskaya; A. Mirshahi; Alex Hewitt; D. Koehn; P.G. Hysi; W.D. Ramdas; T. Zeller; E.N. Vithana; B.K. Cornes; W.-T. Tay; E.S. Tai; C.-Y. Cheng; J. Liu; J.-N. Foo; S.M. Saw; G. Thorleifsson; K. Stefansson; D.P. Dimasi; R.A. Mills; J. Mountain; Wei Ang; R. Hoehn; V.J.M. Verhoeven; F. Grus; R. Wolfs; R. Castagne; K.J. Lackner; H. Springelkamp; J. Yang; F. Jonasson; D.Y.L. Leung; L.J. Chen; C.C.Y. Tham; I. Rudan; Z. Vatavuk; C. Hayward; J. Gibson; A.J. Cree; A. Macleod; S. Ennis; O. Polasek; H. Campbell; J.F. Wilson; A.C. Viswanathan; B. Fleck; X. Li; D. Siscovick; K.D. Taylor; J.I. Rotter; Seyhan Yazar; M. Ulmer; J. Li; B.L. Yaspan; A.B. Ozel; J.E. Richards; S.E. Moroi; J.L. Haines; J.H. Kang; L.R. Pasquale; R.R. Allingham; A. Ashley-Koch; P. Mitchell; J.J. Wang; A.F. Wright; Craig Pennell; T.D. Spector; T.L. Young; C.C.W. Klaver; N.G. Martin; G.W. Montgomery; M.G. Anderson; T. Aung; C.E. Willoughby; J.L. Wiggs; C.P. Pang; U. Thorsteinsdottir; A.J. Lotery; C.J. Hammond; C.M. Van Duijn; M.A. Hauser; Y.S. Rabinowitz; N. Pfeiffer; David Mackey; J.E. Craig; S. Macgregor; T.Y. Wong

doi:10.1038/ng.2506

Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus

Y. Lu, V. Vitart, K.P. Burdon, C.C. Khor, Y. Bykhovskaya, A. Mirshahi, Alex Hewitt, D. Koehn, P.G. Hysi, W.D. Ramdas, T. Zeller, E.N. Vithana, B.K. Cornes, W.-T. Tay, E.S. Tai, C.-Y. Cheng, J. Liu, J.-N. Foo, S.M. Saw, G. ThorleifssonK. Stefansson, D.P. Dimasi, R.A. Mills, J. Mountain, Wei Ang, R. Hoehn, V.J.M. Verhoeven, F. Grus, R. Wolfs, R. Castagne, K.J. Lackner, H. Springelkamp, J. Yang, F. Jonasson, D.Y.L. Leung, L.J. Chen, C.C.Y. Tham, I. Rudan, Z. Vatavuk, C. Hayward, J. Gibson, A.J. Cree, A. Macleod, S. Ennis, O. Polasek, H. Campbell, J.F. Wilson, A.C. Viswanathan, B. Fleck, X. Li, D. Siscovick, K.D. Taylor, J.I. Rotter, Seyhan Yazar, M. Ulmer, J. Li, B.L. Yaspan, A.B. Ozel, J.E. Richards, S.E. Moroi, J.L. Haines, J.H. Kang, L.R. Pasquale, R.R. Allingham, A. Ashley-Koch, P. Mitchell, J.J. Wang, A.F. Wright, Craig Pennell, T.D. Spector, T.L. Young, C.C.W. Klaver, N.G. Martin, G.W. Montgomery, M.G. Anderson, T. Aung, C.E. Willoughby, J.L. Wiggs, C.P. Pang, U. Thorsteinsdottir, A.J. Lotery, C.J. Hammond, C.M. Van Duijn, M.A. Hauser, Y.S. Rabinowitz, N. Pfeiffer, David Mackey, J.E. Craig, S. Macgregor, T.Y. Wong

Research output: Contribution to journal › Article › peer-review

210 Citations (Web of Science)

Original language	English
Pages (from-to)	155
Journal	Nature Genetics
Volume	45
DOIs	https://doi.org/10.1038/ng.2506
Publication status	Published - 2013

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Lu, Y., Vitart, V., Burdon, K. P., Khor, C. C., Bykhovskaya, Y., Mirshahi, A., Hewitt, A., Koehn, D., Hysi, P. G., Ramdas, W. D., Zeller, T., Vithana, E. N., Cornes, B. K., Tay, W-T., Tai, E. S., Cheng, C-Y., Liu, J., Foo, J-N., Saw, S. M., ... Wong, T. Y. (2013). Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus. Nature Genetics, 45, 155. https://doi.org/10.1038/ng.2506

Lu, Y. ; Vitart, V. ; Burdon, K.P. ; Khor, C.C. ; Bykhovskaya, Y. ; Mirshahi, A. ; Hewitt, Alex ; Koehn, D. ; Hysi, P.G. ; Ramdas, W.D. ; Zeller, T. ; Vithana, E.N. ; Cornes, B.K. ; Tay, W.-T. ; Tai, E.S. ; Cheng, C.-Y. ; Liu, J. ; Foo, J.-N. ; Saw, S.M. ; Thorleifsson, G. ; Stefansson, K. ; Dimasi, D.P. ; Mills, R.A. ; Mountain, J. ; Ang, Wei ; Hoehn, R. ; Verhoeven, V.J.M. ; Grus, F. ; Wolfs, R. ; Castagne, R. ; Lackner, K.J. ; Springelkamp, H. ; Yang, J. ; Jonasson, F. ; Leung, D.Y.L. ; Chen, L.J. ; Tham, C.C.Y. ; Rudan, I. ; Vatavuk, Z. ; Hayward, C. ; Gibson, J. ; Cree, A.J. ; Macleod, A. ; Ennis, S. ; Polasek, O. ; Campbell, H. ; Wilson, J.F. ; Viswanathan, A.C. ; Fleck, B. ; Li, X. ; Siscovick, D. ; Taylor, K.D. ; Rotter, J.I. ; Yazar, Seyhan ; Ulmer, M. ; Li, J. ; Yaspan, B.L. ; Ozel, A.B. ; Richards, J.E. ; Moroi, S.E. ; Haines, J.L. ; Kang, J.H. ; Pasquale, L.R. ; Allingham, R.R. ; Ashley-Koch, A. ; Mitchell, P. ; Wang, J.J. ; Wright, A.F. ; Pennell, Craig ; Spector, T.D. ; Young, T.L. ; Klaver, C.C.W. ; Martin, N.G. ; Montgomery, G.W. ; Anderson, M.G. ; Aung, T. ; Willoughby, C.E. ; Wiggs, J.L. ; Pang, C.P. ; Thorsteinsdottir, U. ; Lotery, A.J. ; Hammond, C.J. ; Van Duijn, C.M. ; Hauser, M.A. ; Rabinowitz, Y.S. ; Pfeiffer, N. ; Mackey, David ; Craig, J.E. ; Macgregor, S. ; Wong, T.Y. / Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus. In: Nature Genetics. 2013 ; Vol. 45. pp. 155.

@article{c40c1fcea8a648e99f5702d969175477,

title = "Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus",

author = "Y. Lu and V. Vitart and K.P. Burdon and C.C. Khor and Y. Bykhovskaya and A. Mirshahi and Alex Hewitt and D. Koehn and P.G. Hysi and W.D. Ramdas and T. Zeller and E.N. Vithana and B.K. Cornes and W.-T. Tay and E.S. Tai and C.-Y. Cheng and J. Liu and J.-N. Foo and S.M. Saw and G. Thorleifsson and K. Stefansson and D.P. Dimasi and R.A. Mills and J. Mountain and Wei Ang and R. Hoehn and V.J.M. Verhoeven and F. Grus and R. Wolfs and R. Castagne and K.J. Lackner and H. Springelkamp and J. Yang and F. Jonasson and D.Y.L. Leung and L.J. Chen and C.C.Y. Tham and I. Rudan and Z. Vatavuk and C. Hayward and J. Gibson and A.J. Cree and A. Macleod and S. Ennis and O. Polasek and H. Campbell and J.F. Wilson and A.C. Viswanathan and B. Fleck and X. Li and D. Siscovick and K.D. Taylor and J.I. Rotter and Seyhan Yazar and M. Ulmer and J. Li and B.L. Yaspan and A.B. Ozel and J.E. Richards and S.E. Moroi and J.L. Haines and J.H. Kang and L.R. Pasquale and R.R. Allingham and A. Ashley-Koch and P. Mitchell and J.J. Wang and A.F. Wright and Craig Pennell and T.D. Spector and T.L. Young and C.C.W. Klaver and N.G. Martin and G.W. Montgomery and M.G. Anderson and T. Aung and C.E. Willoughby and J.L. Wiggs and C.P. Pang and U. Thorsteinsdottir and A.J. Lotery and C.J. Hammond and {Van Duijn}, C.M. and M.A. Hauser and Y.S. Rabinowitz and N. Pfeiffer and David Mackey and J.E. Craig and S. Macgregor and T.Y. Wong",

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doi = "10.1038/ng.2506",

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pages = "155",

journal = "Nature Genetics",

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Lu, Y, Vitart, V, Burdon, KP, Khor, CC, Bykhovskaya, Y, Mirshahi, A, Hewitt, A, Koehn, D, Hysi, PG, Ramdas, WD, Zeller, T, Vithana, EN, Cornes, BK, Tay, W-T, Tai, ES, Cheng, C-Y, Liu, J, Foo, J-N, Saw, SM, Thorleifsson, G, Stefansson, K, Dimasi, DP, Mills, RA, Mountain, J, Ang, W, Hoehn, R, Verhoeven, VJM, Grus, F, Wolfs, R, Castagne, R, Lackner, KJ, Springelkamp, H, Yang, J, Jonasson, F, Leung, DYL, Chen, LJ, Tham, CCY, Rudan, I, Vatavuk, Z, Hayward, C, Gibson, J, Cree, AJ, Macleod, A, Ennis, S, Polasek, O, Campbell, H, Wilson, JF, Viswanathan, AC, Fleck, B, Li, X, Siscovick, D, Taylor, KD, Rotter, JI, Yazar, S, Ulmer, M, Li, J, Yaspan, BL, Ozel, AB, Richards, JE, Moroi, SE, Haines, JL, Kang, JH, Pasquale, LR, Allingham, RR, Ashley-Koch, A, Mitchell, P, Wang, JJ, Wright, AF, Pennell, C, Spector, TD, Young, TL, Klaver, CCW, Martin, NG, Montgomery, GW, Anderson, MG, Aung, T, Willoughby, CE, Wiggs, JL, Pang, CP, Thorsteinsdottir, U, Lotery, AJ, Hammond, CJ, Van Duijn, CM, Hauser, MA, Rabinowitz, YS, Pfeiffer, N, Mackey, D, Craig, JE, Macgregor, S & Wong, TY 2013, 'Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus', Nature Genetics, vol. 45, pp. 155. https://doi.org/10.1038/ng.2506

Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus. / Lu, Y.; Vitart, V.; Burdon, K.P.; Khor, C.C.; Bykhovskaya, Y.; Mirshahi, A.; Hewitt, Alex; Koehn, D.; Hysi, P.G.; Ramdas, W.D.; Zeller, T.; Vithana, E.N.; Cornes, B.K.; Tay, W.-T.; Tai, E.S.; Cheng, C.-Y.; Liu, J.; Foo, J.-N.; Saw, S.M.; Thorleifsson, G.; Stefansson, K.; Dimasi, D.P.; Mills, R.A.; Mountain, J.; Ang, Wei; Hoehn, R.; Verhoeven, V.J.M.; Grus, F.; Wolfs, R.; Castagne, R.; Lackner, K.J.; Springelkamp, H.; Yang, J.; Jonasson, F.; Leung, D.Y.L.; Chen, L.J.; Tham, C.C.Y.; Rudan, I.; Vatavuk, Z.; Hayward, C.; Gibson, J.; Cree, A.J.; Macleod, A.; Ennis, S.; Polasek, O.; Campbell, H.; Wilson, J.F.; Viswanathan, A.C.; Fleck, B.; Li, X.; Siscovick, D.; Taylor, K.D.; Rotter, J.I.; Yazar, Seyhan; Ulmer, M.; Li, J.; Yaspan, B.L.; Ozel, A.B.; Richards, J.E.; Moroi, S.E.; Haines, J.L.; Kang, J.H.; Pasquale, L.R.; Allingham, R.R.; Ashley-Koch, A.; Mitchell, P.; Wang, J.J.; Wright, A.F.; Pennell, Craig; Spector, T.D.; Young, T.L.; Klaver, C.C.W.; Martin, N.G.; Montgomery, G.W.; Anderson, M.G.; Aung, T.; Willoughby, C.E.; Wiggs, J.L.; Pang, C.P.; Thorsteinsdottir, U.; Lotery, A.J.; Hammond, C.J.; Van Duijn, C.M.; Hauser, M.A.; Rabinowitz, Y.S.; Pfeiffer, N.; Mackey, David; Craig, J.E.; Macgregor, S.; Wong, T.Y.

In: Nature Genetics, Vol. 45, 2013, p. 155.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus

AU - Lu, Y.

AU - Vitart, V.

AU - Burdon, K.P.

AU - Khor, C.C.

AU - Bykhovskaya, Y.

AU - Mirshahi, A.

AU - Hewitt, Alex

AU - Koehn, D.

AU - Hysi, P.G.

AU - Ramdas, W.D.

AU - Zeller, T.

AU - Vithana, E.N.

AU - Cornes, B.K.

AU - Tay, W.-T.

AU - Tai, E.S.

AU - Cheng, C.-Y.

AU - Liu, J.

AU - Foo, J.-N.

AU - Saw, S.M.

AU - Thorleifsson, G.

AU - Stefansson, K.

AU - Dimasi, D.P.

AU - Mills, R.A.

AU - Mountain, J.

AU - Ang, Wei

AU - Hoehn, R.

AU - Verhoeven, V.J.M.

AU - Grus, F.

AU - Wolfs, R.

AU - Castagne, R.

AU - Lackner, K.J.

AU - Springelkamp, H.

AU - Yang, J.

AU - Jonasson, F.

AU - Leung, D.Y.L.

AU - Chen, L.J.

AU - Tham, C.C.Y.

AU - Rudan, I.

AU - Vatavuk, Z.

AU - Hayward, C.

AU - Gibson, J.

AU - Cree, A.J.

AU - Macleod, A.

AU - Ennis, S.

AU - Polasek, O.

AU - Campbell, H.

AU - Wilson, J.F.

AU - Viswanathan, A.C.

AU - Fleck, B.

AU - Li, X.

AU - Siscovick, D.

AU - Taylor, K.D.

AU - Rotter, J.I.

AU - Yazar, Seyhan

AU - Ulmer, M.

AU - Li, J.

AU - Yaspan, B.L.

AU - Ozel, A.B.

AU - Richards, J.E.

AU - Moroi, S.E.

AU - Haines, J.L.

AU - Kang, J.H.

AU - Pasquale, L.R.

AU - Allingham, R.R.

AU - Ashley-Koch, A.

AU - Mitchell, P.

AU - Wang, J.J.

AU - Wright, A.F.

AU - Pennell, Craig

AU - Spector, T.D.

AU - Young, T.L.

AU - Klaver, C.C.W.

AU - Martin, N.G.

AU - Montgomery, G.W.

AU - Anderson, M.G.

AU - Aung, T.

AU - Willoughby, C.E.

AU - Wiggs, J.L.

AU - Pang, C.P.

AU - Thorsteinsdottir, U.

AU - Lotery, A.J.

AU - Hammond, C.J.

AU - Van Duijn, C.M.

AU - Hauser, M.A.

AU - Rabinowitz, Y.S.

AU - Pfeiffer, N.

AU - Mackey, David

AU - Craig, J.E.

AU - Macgregor, S.

AU - Wong, T.Y.

PY - 2013

Y1 - 2013

U2 - 10.1038/ng.2506

DO - 10.1038/ng.2506

M3 - Article

VL - 45

SP - 155

JO - Nature Genetics

JF - Nature Genetics

SN - 1061-4036

ER -