Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma

P.G. Hysi; C.-Y. Cheng; H. Springelkamp; S. Macgregor; J.N.C. Bailey; R. Wojciechowski; V. Vitart; A. Nag; A.W. Hewitt; R. Höhn; C. Venturini; A. Mirshahi; W.D. Ramdas; G. Thorleifsson; E. Vithana; C.-C. Khor; A.B. Stefansson; J. Liao; J.L. Haines; N. Amin; Y.X. Wang; P.S. Wild; A.B. Ozel; J.Z. Li; B.W. Fleck; T. Zeller; S.E. Staffieri; Y.-Y. Teo; G. Cuellar-Partida; X. Luo; R.R. Allingham; J.E. Richards; A. Senft; L.C. Karssen; Y. Zheng; C. Bellenguez; L. Xu; A.I. Iglesias; J.F. Wilson; J.H. Kang; E.M. Van Leeuwen; V. Jonsson; U. Thorsteinsdottir; D.D.G. Despriet; S. Ennis; S.E. Moroi; N.G. Martin; N.M. Jansonius; S. Yazar; E.-S. Tai; P. Amouyel; J. Kirwan; L.M.E. Van Koolwijk; M.A. Hauser; F. Jonasson; P. Leo; S.J. Loomis; R. Fogarty; F. Rivadeneira; L. Kearns; K.J. Lackner; P.T.V.M. De Jong; C.L. Simpson; Craig Pennell; B.A. Oostra; A.G. Uitterlinden; S.-M. Saw; A.J. Lotery; J.E. Bailey-Wilson; A. Hofman; J.R. Vingerling; C. Maubaret; N. Pfeiffer; R.C.W. Wolfs; H.G. Lemij; T.L. Young; L.R. Pasquale; C. Delcourt; T.D. Spector; C.C.W. Klaver; K.S. Small; K.P. Burdon; K. Stefansson; T.-Y. Wong; A. Viswanathan; David Mackey; J.E. Craig; J.L. Wiggs; C.M. Van Duijn; C.J. Hammond; T. Aung

doi:10.1038/ng.3087

Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma

P.G. Hysi, C.-Y. Cheng, H. Springelkamp, S. Macgregor, J.N.C. Bailey, R. Wojciechowski, V. Vitart, A. Nag, A.W. Hewitt, R. Höhn, C. Venturini, A. Mirshahi, W.D. Ramdas, G. Thorleifsson, E. Vithana, C.-C. Khor, A.B. Stefansson, J. Liao, J.L. Haines, N. AminY.X. Wang, P.S. Wild, A.B. Ozel, J.Z. Li, B.W. Fleck, T. Zeller, S.E. Staffieri, Y.-Y. Teo, G. Cuellar-Partida, X. Luo, R.R. Allingham, J.E. Richards, A. Senft, L.C. Karssen, Y. Zheng, C. Bellenguez, L. Xu, A.I. Iglesias, J.F. Wilson, J.H. Kang, E.M. Van Leeuwen, V. Jonsson, U. Thorsteinsdottir, D.D.G. Despriet, S. Ennis, S.E. Moroi, N.G. Martin, N.M. Jansonius, S. Yazar, E.-S. Tai, P. Amouyel, J. Kirwan, L.M.E. Van Koolwijk, M.A. Hauser, F. Jonasson, P. Leo, S.J. Loomis, R. Fogarty, F. Rivadeneira, L. Kearns, K.J. Lackner, P.T.V.M. De Jong, C.L. Simpson, Craig Pennell, B.A. Oostra, A.G. Uitterlinden, S.-M. Saw, A.J. Lotery, J.E. Bailey-Wilson, A. Hofman, J.R. Vingerling, C. Maubaret, N. Pfeiffer, R.C.W. Wolfs, H.G. Lemij, T.L. Young, L.R. Pasquale, C. Delcourt, T.D. Spector, C.C.W. Klaver, K.S. Small, K.P. Burdon, K. Stefansson, T.-Y. Wong, A. Viswanathan, David Mackey, J.E. Craig, J.L. Wiggs, C.M. Van Duijn, C.J. Hammond, T. Aung

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205 Citations (Scopus)

Original language	English
Pages (from-to)	1126
Journal	Nature Genetics
Volume	46
DOIs	https://doi.org/10.1038/ng.3087
Publication status	Published - 2014

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Hysi, P. G., Cheng, C.-Y., Springelkamp, H., Macgregor, S., Bailey, J. N. C., Wojciechowski, R., Vitart, V., Nag, A., Hewitt, A. W., Höhn, R., Venturini, C., Mirshahi, A., Ramdas, W. D., Thorleifsson, G., Vithana, E., Khor, C.-C., Stefansson, A. B., Liao, J., Haines, J. L., ... Aung, T. (2014). Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma. Nature Genetics, 46, 1126. https://doi.org/10.1038/ng.3087

@article{6e59e9b8077a4ed1b89cb2f12281a9f4,

title = "Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma",

author = "P.G. Hysi and C.-Y. Cheng and H. Springelkamp and S. Macgregor and J.N.C. Bailey and R. Wojciechowski and V. Vitart and A. Nag and A.W. Hewitt and R. H{\"o}hn and C. Venturini and A. Mirshahi and W.D. Ramdas and G. Thorleifsson and E. Vithana and C.-C. Khor and A.B. Stefansson and J. Liao and J.L. Haines and N. Amin and Y.X. Wang and P.S. Wild and A.B. Ozel and J.Z. Li and B.W. Fleck and T. Zeller and S.E. Staffieri and Y.-Y. Teo and G. Cuellar-Partida and X. Luo and R.R. Allingham and J.E. Richards and A. Senft and L.C. Karssen and Y. Zheng and C. Bellenguez and L. Xu and A.I. Iglesias and J.F. Wilson and J.H. Kang and {Van Leeuwen}, E.M. and V. Jonsson and U. Thorsteinsdottir and D.D.G. Despriet and S. Ennis and S.E. Moroi and N.G. Martin and N.M. Jansonius and S. Yazar and E.-S. Tai and P. Amouyel and J. Kirwan and {Van Koolwijk}, L.M.E. and M.A. Hauser and F. Jonasson and P. Leo and S.J. Loomis and R. Fogarty and F. Rivadeneira and L. Kearns and K.J. Lackner and {De Jong}, P.T.V.M. and C.L. Simpson and Craig Pennell and B.A. Oostra and A.G. Uitterlinden and S.-M. Saw and A.J. Lotery and J.E. Bailey-Wilson and A. Hofman and J.R. Vingerling and C. Maubaret and N. Pfeiffer and R.C.W. Wolfs and H.G. Lemij and T.L. Young and L.R. Pasquale and C. Delcourt and T.D. Spector and C.C.W. Klaver and K.S. Small and K.P. Burdon and K. Stefansson and T.-Y. Wong and A. Viswanathan and David Mackey and J.E. Craig and J.L. Wiggs and {Van Duijn}, C.M. and C.J. Hammond and T. Aung",

year = "2014",

doi = "10.1038/ng.3087",

language = "English",

volume = "46",

pages = "1126",

journal = "Nature Genetics",

issn = "1061-4036",

publisher = "Nature Publishing Group - Macmillan Publishers",

}

Hysi, PG, Cheng, C-Y, Springelkamp, H, Macgregor, S, Bailey, JNC, Wojciechowski, R, Vitart, V, Nag, A, Hewitt, AW, Höhn, R, Venturini, C, Mirshahi, A, Ramdas, WD, Thorleifsson, G, Vithana, E, Khor, C-C, Stefansson, AB, Liao, J, Haines, JL, Amin, N, Wang, YX, Wild, PS, Ozel, AB, Li, JZ, Fleck, BW, Zeller, T, Staffieri, SE, Teo, Y-Y, Cuellar-Partida, G, Luo, X, Allingham, RR, Richards, JE, Senft, A, Karssen, LC, Zheng, Y, Bellenguez, C, Xu, L, Iglesias, AI, Wilson, JF, Kang, JH, Van Leeuwen, EM, Jonsson, V, Thorsteinsdottir, U, Despriet, DDG, Ennis, S, Moroi, SE, Martin, NG, Jansonius, NM, Yazar, S, Tai, E-S, Amouyel, P, Kirwan, J, Van Koolwijk, LME, Hauser, MA, Jonasson, F, Leo, P, Loomis, SJ, Fogarty, R, Rivadeneira, F, Kearns, L, Lackner, KJ, De Jong, PTVM, Simpson, CL, Pennell, C, Oostra, BA, Uitterlinden, AG, Saw, S-M, Lotery, AJ, Bailey-Wilson, JE, Hofman, A, Vingerling, JR, Maubaret, C, Pfeiffer, N, Wolfs, RCW, Lemij, HG, Young, TL, Pasquale, LR, Delcourt, C, Spector, TD, Klaver, CCW, Small, KS, Burdon, KP, Stefansson, K, Wong, T-Y, Viswanathan, A, Mackey, D, Craig, JE, Wiggs, JL, Van Duijn, CM, Hammond, CJ & Aung, T 2014, 'Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma', Nature Genetics, vol. 46, pp. 1126. https://doi.org/10.1038/ng.3087

TY - JOUR

T1 - Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma

AU - Hysi, P.G.

AU - Cheng, C.-Y.

AU - Springelkamp, H.

AU - Macgregor, S.

AU - Bailey, J.N.C.

AU - Wojciechowski, R.

AU - Vitart, V.

AU - Nag, A.

AU - Hewitt, A.W.

AU - Höhn, R.

AU - Venturini, C.

AU - Mirshahi, A.

AU - Ramdas, W.D.

AU - Thorleifsson, G.

AU - Vithana, E.

AU - Khor, C.-C.

AU - Stefansson, A.B.

AU - Liao, J.

AU - Haines, J.L.

AU - Amin, N.

AU - Wang, Y.X.

AU - Wild, P.S.

AU - Ozel, A.B.

AU - Li, J.Z.

AU - Fleck, B.W.

AU - Zeller, T.

AU - Staffieri, S.E.

AU - Teo, Y.-Y.

AU - Cuellar-Partida, G.

AU - Luo, X.

AU - Allingham, R.R.

AU - Richards, J.E.

AU - Senft, A.

AU - Karssen, L.C.

AU - Zheng, Y.

AU - Bellenguez, C.

AU - Xu, L.

AU - Iglesias, A.I.

AU - Wilson, J.F.

AU - Kang, J.H.

AU - Van Leeuwen, E.M.

AU - Jonsson, V.

AU - Thorsteinsdottir, U.

AU - Despriet, D.D.G.

AU - Ennis, S.

AU - Moroi, S.E.

AU - Martin, N.G.

AU - Jansonius, N.M.

AU - Yazar, S.

AU - Tai, E.-S.

AU - Amouyel, P.

AU - Kirwan, J.

AU - Van Koolwijk, L.M.E.

AU - Hauser, M.A.

AU - Jonasson, F.

AU - Leo, P.

AU - Loomis, S.J.

AU - Fogarty, R.

AU - Rivadeneira, F.

AU - Kearns, L.

AU - Lackner, K.J.

AU - De Jong, P.T.V.M.

AU - Simpson, C.L.

AU - Pennell, Craig

AU - Oostra, B.A.

AU - Uitterlinden, A.G.

AU - Saw, S.-M.

AU - Lotery, A.J.

AU - Bailey-Wilson, J.E.

AU - Hofman, A.

AU - Vingerling, J.R.

AU - Maubaret, C.

AU - Pfeiffer, N.

AU - Wolfs, R.C.W.

AU - Lemij, H.G.

AU - Young, T.L.

AU - Pasquale, L.R.

AU - Delcourt, C.

AU - Spector, T.D.

AU - Klaver, C.C.W.

AU - Small, K.S.

AU - Burdon, K.P.

AU - Stefansson, K.

AU - Wong, T.-Y.

AU - Viswanathan, A.

AU - Mackey, David

AU - Craig, J.E.

AU - Wiggs, J.L.

AU - Van Duijn, C.M.

AU - Hammond, C.J.

AU - Aung, T.

PY - 2014

Y1 - 2014

U2 - 10.1038/ng.3087

DO - 10.1038/ng.3087

M3 - Article

C2 - 25173106

SN - 1061-4036

VL - 46

SP - 1126

JO - Nature Genetics

JF - Nature Genetics

ER -