TY - JOUR
T1 - Genetic characterization of archived bunyaviruses and their potential for emergence in Australia
AU - Huang, B.
AU - Firth, C.
AU - Watterson, D.
AU - Allcock, Richard
AU - Colmant, A.M.G.
AU - Hobson-Peters, J.
AU - Kirkland, P.
AU - Hewitson, G.
AU - Mcmahon, J.
AU - Hall-Mendelin, S.
AU - Van Den Hurk, A.F.
AU - Warrilow, D.
PY - 2016/5
Y1 - 2016/5
N2 - © 2016, Centers for Disease Control and Prevention (CDC). All rights reserved. To better understand the diversity of bunyaviruses and their circulation in Australia, we sequenced 5 viruses (Gan Gan, Trubanaman, Kowanyama, Yacaaba, and Taggert) isolated and serologically identified 4 decades ago as members of the family Bunyaviridae. Gan Gan and Trubanaman viruses almost perfectly matched 2 recently isolated, purportedly novel viruses, Salt Ash and Murrumbidgee viruses, respectively. Kowanyama and Yacaaba viruses were identified as being related to members of a large clade containing pathogenic viruses. Taggert virus was confirmed as being a nairovirus; several viruses of this genus are pathogenic to humans. The genetic relationships and historical experimental infections in mice reveal the potential for these viruses to lead to disease emergence.
AB - © 2016, Centers for Disease Control and Prevention (CDC). All rights reserved. To better understand the diversity of bunyaviruses and their circulation in Australia, we sequenced 5 viruses (Gan Gan, Trubanaman, Kowanyama, Yacaaba, and Taggert) isolated and serologically identified 4 decades ago as members of the family Bunyaviridae. Gan Gan and Trubanaman viruses almost perfectly matched 2 recently isolated, purportedly novel viruses, Salt Ash and Murrumbidgee viruses, respectively. Kowanyama and Yacaaba viruses were identified as being related to members of a large clade containing pathogenic viruses. Taggert virus was confirmed as being a nairovirus; several viruses of this genus are pathogenic to humans. The genetic relationships and historical experimental infections in mice reveal the potential for these viruses to lead to disease emergence.
U2 - 10.3201/eid2205.151566
DO - 10.3201/eid2205.151566
M3 - Article
C2 - 27088588
VL - 22
SP - 833
EP - 840
JO - Emerging Infectious Diseases
JF - Emerging Infectious Diseases
SN - 1080-6040
IS - 5
ER -