Genetic characterization of archived bunyaviruses and their potential for emergence in Australia

B. Huang, C. Firth, D. Watterson, Richard Allcock, A.M.G. Colmant, J. Hobson-Peters, P. Kirkland, G. Hewitson, J. Mcmahon, S. Hall-Mendelin, A.F. Van Den Hurk, D. Warrilow

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Abstract

© 2016, Centers for Disease Control and Prevention (CDC). All rights reserved. To better understand the diversity of bunyaviruses and their circulation in Australia, we sequenced 5 viruses (Gan Gan, Trubanaman, Kowanyama, Yacaaba, and Taggert) isolated and serologically identified 4 decades ago as members of the family Bunyaviridae. Gan Gan and Trubanaman viruses almost perfectly matched 2 recently isolated, purportedly novel viruses, Salt Ash and Murrumbidgee viruses, respectively. Kowanyama and Yacaaba viruses were identified as being related to members of a large clade containing pathogenic viruses. Taggert virus was confirmed as being a nairovirus; several viruses of this genus are pathogenic to humans. The genetic relationships and historical experimental infections in mice reveal the potential for these viruses to lead to disease emergence.
Original languageEnglish
Pages (from-to)833-840
JournalEmerging Infectious Diseases
Volume22
Issue number5
DOIs
Publication statusPublished - 2016

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Huang, B., Firth, C., Watterson, D., Allcock, R., Colmant, A. M. G., Hobson-Peters, J., ... Warrilow, D. (2016). Genetic characterization of archived bunyaviruses and their potential for emergence in Australia. Emerging Infectious Diseases, 22(5), 833-840. https://doi.org/10.3201/eid2205.151566