To protect crops against herbicide damage and maximize crop yields, we must develop crop varieties with high herbicide tolerance. My research revealed large genetic variability for pre-emergent metribuzin tolerance in wheat (https://doi.org/10.1071/CP17017). The genetics of metribuzin tolerance in wheat (https://doi.org/10.1186/s12870-019-2070-x) fits an additive-dominance model model which is valuable information to plant breeders and wheat producers worldwide. QLT mapping (https://rdcu.be/bbLTp) and wheat 90K SNP chip (https://doi.org/10.1186/s12870-019-2070-x) identified genomic regions and candidate genes responsible for metribuzin tolerance. Transcriptome sequencing revealed key genes, mechanisms, and novel EST-SSR markers associated with metribuzin tolerance. These resources provide promising avenues for metribuzin tolerance breeding in wheat.