Genesis of the frog retinal pigment epithelium

Lyn Beazley; S.A. Dunlop; Marc Tennant; T.L. Tomlin; J.M. Preuss; Sarah Coleman

doi:10.1016/0165-3806(96)00125-3

Genesis of the frog retinal pigment epithelium

Lyn Beazley
, S.A. Dunlop
, Marc Tennant
, T.L. Tomlin
, J.M. Preuss
, Sarah Coleman

Institute of Advanced Studies

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

To examine cell generation in the frog retinal pigment epithelium (RPE), representative developmental stages from tail-bud to adulthood received a single injection of [H-3]thymidine. Animals were killed either 24 h or several weeks later; eyes were sectioned and processed by standard autoradiographic procedures and viewed by epi-polarised illumination. The distribution of [H-3]thymidine-labelled cells indicated that the RPE is formed throughout life, including in adulthood, by cell addition at the ciliary margin, matching the pattern for the neural retina. In addition, a very small number of peripapillary RPE cells underwent division but only in the adult.

Original language	English
Pages (from-to)	290-294
Journal	Developmental Brain Research
Volume	96
DOIs	https://doi.org/10.1016/0165-3806(96)00125-3
Publication status	Published - 1996

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title = "Genesis of the frog retinal pigment epithelium",

abstract = "To examine cell generation in the frog retinal pigment epithelium (RPE), representative developmental stages from tail-bud to adulthood received a single injection of [H-3]thymidine. Animals were killed either 24 h or several weeks later; eyes were sectioned and processed by standard autoradiographic procedures and viewed by epi-polarised illumination. The distribution of [H-3]thymidine-labelled cells indicated that the RPE is formed throughout life, including in adulthood, by cell addition at the ciliary margin, matching the pattern for the neural retina. In addition, a very small number of peripapillary RPE cells underwent division but only in the adult.",

author = "Lyn Beazley and S.A. Dunlop and Marc Tennant and T.L. Tomlin and J.M. Preuss and Sarah Coleman",

year = "1996",

doi = "10.1016/0165-3806(96)00125-3",

language = "English",

volume = "96",

pages = "290--294",

journal = "Developmental Brain Research",

publisher = "Elsevier",

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T1 - Genesis of the frog retinal pigment epithelium

AU - Beazley, Lyn

AU - Dunlop, S.A.

AU - Tennant, Marc

AU - Tomlin, T.L.

AU - Preuss, J.M.

AU - Coleman, Sarah

PY - 1996

Y1 - 1996

N2 - To examine cell generation in the frog retinal pigment epithelium (RPE), representative developmental stages from tail-bud to adulthood received a single injection of [H-3]thymidine. Animals were killed either 24 h or several weeks later; eyes were sectioned and processed by standard autoradiographic procedures and viewed by epi-polarised illumination. The distribution of [H-3]thymidine-labelled cells indicated that the RPE is formed throughout life, including in adulthood, by cell addition at the ciliary margin, matching the pattern for the neural retina. In addition, a very small number of peripapillary RPE cells underwent division but only in the adult.

AB - To examine cell generation in the frog retinal pigment epithelium (RPE), representative developmental stages from tail-bud to adulthood received a single injection of [H-3]thymidine. Animals were killed either 24 h or several weeks later; eyes were sectioned and processed by standard autoradiographic procedures and viewed by epi-polarised illumination. The distribution of [H-3]thymidine-labelled cells indicated that the RPE is formed throughout life, including in adulthood, by cell addition at the ciliary margin, matching the pattern for the neural retina. In addition, a very small number of peripapillary RPE cells underwent division but only in the adult.

U2 - 10.1016/0165-3806(96)00125-3

DO - 10.1016/0165-3806(96)00125-3

M3 - Article

VL - 96

SP - 290

EP - 294

JO - Developmental Brain Research

JF - Developmental Brain Research

ER -

Genesis of the frog retinal pigment epithelium

Abstract

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