Projects per year
The human iPSC lines LEIi010-A and LEIi010-B were generated from the dermal fibroblasts of a patient with Usher syndrome using episomal plasmids containing OCT4, SOX2, KLF4, L-MYC, LIN28, mir302/367 microRNA and shRNA for p53. These iPSC lines carry compound heterozygous mutations (c.949C > A and c.1256G > T) in USH2A. LEIi010-A and LEIi010-B expressed pluripotent stem cell markers, had a normal karyotype and could be differentiated into endoderm, mesoderm and ectodermal lineages.
FingerprintDive into the research topics of 'Generation of two induced pluripotent stem cell lines from a patient with compound heterozygous mutations in the USH2A gene'. Together they form a unique fingerprint.
- 2 Finished
1/01/18 → 31/12/21