Generalising a Simple Methodology for the Regioselective Anomeric Deacetylation of Carbohydrates

Mitchell Hattie; Keith A. Stubbs

doi:10.1002/slct.201904343

Generalising a Simple Methodology for the Regioselective Anomeric Deacetylation of Carbohydrates

Mitchell Hattie, Keith A. Stubbs

School of Molecular Sciences

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

148 Downloads (Pure)

Abstract

The use of methylamine to deprotect 1-O-acetyl protected carbohydrates has only attracted limited interest in the literature. Demonstrated here is an approach that is able to be generalized for a wide variety of carbohydrate scaffolds which results in a high yielding, simplified, practical, expedient and clean method to prepare hemiacetals from 1-O-acetyl protected carbohydrates.

Original language	English
Pages (from-to)	875-877
Number of pages	3
Journal	ChemistrySelect
Volume	5
Issue number	2
DOIs	https://doi.org/10.1002/slct.201904343
Publication status	Published - 16 Jan 2020

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10.1002/slct.201904343

Hattie & Stubbs, 2020 Generalising a Simple Methodology for the Regioselective Anomeric Deacetylation of CarbohydratesAccepted author manuscript, 277 KB

Cite this

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title = "Generalising a Simple Methodology for the Regioselective Anomeric Deacetylation of Carbohydrates",

abstract = "The use of methylamine to deprotect 1-O-acetyl protected carbohydrates has only attracted limited interest in the literature. Demonstrated here is an approach that is able to be generalized for a wide variety of carbohydrate scaffolds which results in a high yielding, simplified, practical, expedient and clean method to prepare hemiacetals from 1-O-acetyl protected carbohydrates.",

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KW - Protecting Groups

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Generalising a Simple Methodology for the Regioselective Anomeric Deacetylation of Carbohydrates

Abstract

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The Development of Tools to Study Carbohydrate-Processing Enzymes Implicated in Human Disease

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Generalising a Simple Methodology for the Regioselective Anomeric Deacetylation of Carbohydrates

Abstract

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The Development of Tools to Study Carbohydrate-Processing Enzymes Implicated in Human Disease

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