TY - JOUR
T1 - Gastric adenocarcinoma presenting as uterine metastasis - A case report
AU - Tsoi, D.
AU - Buck, M.
AU - Hammond, Ian
AU - White, J.
PY - 2005
Y1 - 2005
N2 - Background. Metastases to the uterus are rare, especially from extrapelvic malignancies.Case. We report a 75-year-old woman who underwent hysterectomy for a FIGO Grade I endometrial carcinoma and was found to have evidence of a second malignant process involving the myometrium. The patient underwent a gastroscopy, which showed nonspecific superficial gastric and duodenal erosions. Random biopsies, however, confirmed a diagnosis of primary gastric adenocarcinoma. CT scan also showed pulmonary metastasis. The patient developed progressive disease despite two cycles of chemotherapy consistent of etoposide, doxorubicin and carboplatin.Conclusion. This case illustrates the presence of two spatially separated tumours found in the uterus. Malignant cells present deep in the lymphovascular spaces have morphological features different from the primary endometrial carcinoma. The microscopic appearances of these cells are similar to that of the gastric biopsy, supporting the diagnosis of metastatic gastric adenocarcinoma. (c) 2005 Elsevier Inc. All rights reserved.
AB - Background. Metastases to the uterus are rare, especially from extrapelvic malignancies.Case. We report a 75-year-old woman who underwent hysterectomy for a FIGO Grade I endometrial carcinoma and was found to have evidence of a second malignant process involving the myometrium. The patient underwent a gastroscopy, which showed nonspecific superficial gastric and duodenal erosions. Random biopsies, however, confirmed a diagnosis of primary gastric adenocarcinoma. CT scan also showed pulmonary metastasis. The patient developed progressive disease despite two cycles of chemotherapy consistent of etoposide, doxorubicin and carboplatin.Conclusion. This case illustrates the presence of two spatially separated tumours found in the uterus. Malignant cells present deep in the lymphovascular spaces have morphological features different from the primary endometrial carcinoma. The microscopic appearances of these cells are similar to that of the gastric biopsy, supporting the diagnosis of metastatic gastric adenocarcinoma. (c) 2005 Elsevier Inc. All rights reserved.
U2 - 10.1016/j.ygyno.2005.01.055
DO - 10.1016/j.ygyno.2005.01.055
M3 - Review article
C2 - 15943994
SN - 0090-8258
VL - 97
SP - 932
EP - 934
JO - Gynecologic Oncology
JF - Gynecologic Oncology
ER -