Abstract
Gallium metal is effective in mediating the allylation of various carbonyl compounds and imines under solvent-free conditions, with the application of sonic energy, affording the corresponding homoallylic alcohols and amines. The imines themselves were also prepared under solventless conditions in high yield, thereby establishing a two-step solvent-free synthesis of homoallylic amines. In comparison, indium metal produced a mixture of the desired homoallylic secondary amine and the bisallylated species via an iminium ion intermediate. (C) 2003 Elsevier Ltd. All rights reserved.
Original language | English |
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Pages (from-to) | 243-248 |
Journal | Tetrahedron Letters |
Volume | 45 |
Issue number | 2 |
DOIs | |
Publication status | Published - 2004 |