Functional respiratory imaging as a tool to personalize respiratory treatment in patients with unilateral diaphragmatic paralysis

Cedric S. Van Holsbeke, Glenn Leemans, Wim G. Vos, Jan W. De Backer, Samir C. Vinchurkar, Michel Geldof, Pascal R. Verdonck, Paul M. Parizel, Paul E. Van Schil, Wilfried A. De Backer

Research output: Contribution to journalShort survey

6 Citations (Scopus)

Abstract

A completely different treatment approach was chosen for 2 patients with unilateral diaphragmatic paralysis and complaints of dyspnea despite similar anatomic and physiologic abnormalities. These decisions were supported by results obtained by functional respiratory imaging (FRI). FRI generated functional information on lobar ventilation and local drug deposition. In the first patient, some lobes were poorly ventilated, and drug deposition simulation showed that some regions were undertreated. This patient underwent diaphragmatic plication to restore ventilation. In the second patient, all lobes were still ventilated. A conservative approach with regular follow-ups was chosen to wait for spontaneous recovery of the diaphragmatic function. Both patients improved subjectively and objectively. These cases demonstrate how novel medical imaging techniques such as FRI can be used to personalize respiratory treatment in patients with unilateral diaphragmatic paralysis.

Original languageEnglish
Pages (from-to)e127-e131
JournalRespiratory Care
Volume59
Issue number9
DOIs
Publication statusPublished - 1 Sep 2014
Externally publishedYes

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    Van Holsbeke, C. S., Leemans, G., Vos, W. G., De Backer, J. W., Vinchurkar, S. C., Geldof, M., Verdonck, P. R., Parizel, P. M., Van Schil, P. E., & De Backer, W. A. (2014). Functional respiratory imaging as a tool to personalize respiratory treatment in patients with unilateral diaphragmatic paralysis. Respiratory Care, 59(9), e127-e131. https://doi.org/10.4187/respcare.02756