Functional imaging of the skin vasculature at the microscale in humans: Optical coherence tomography in diabetes and the impact of exercise training

Research output: ThesisDoctoral Thesis

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Abstract

This thesis developed a novel technique for assessment of microvessel structure and function in humans utilizing optical coherence tomography (OCT). This non-invasive technology is capable of directly visualizing and quantifying microvessels and, when combined with physiological testing, revealed abnormalities in the skin of diabetic subjects. It was also deployed to assess microvascular adaptation in response to exercise training. This thesis suggests that OCT is an accurate and robust technique capable of imaging and quantifying microvascular function and structure in humans, with promising future applications in human cardiovascular health and disease.
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • The University of Western Australia
Supervisors/Advisors
  • Green, Daniel, Supervisor
  • Ackland, Tim, Supervisor
  • Naylor, Louise, Supervisor
  • Jansen, Shirley, Supervisor
Award date7 Oct 2021
DOIs
Publication statusUnpublished - 2021

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