Forensic applications of the genomic matching technique: Profiling the alpha block in the major histocompatibility complex

R. Laird, R. L. Dawkins, N. Jacobsen, S. Gaudieri

Research output: Contribution to journalArticlepeer-review

Abstract

The genomic matching technique (GMT) was developed to characterize polymorphic sequences within the human major histocompatibility complex (MHC), known as polymorphic frozen blocks (PFBs). PFBs are 200–300 kb sequences containing duplications, indels and SNPs. The power of the GMT to differentiate between individuals at the DNA level means that it can be applied as an exclusion tool in forensic science. Here, the GMT is applied to the alpha block in the MHC.

Original languageEnglish
Pages (from-to)580-582
Number of pages3
JournalInternational Congress Series
Volume1261
Issue numberC
DOIs
Publication statusPublished - 1 Apr 2004

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