Focal cerebral ischaemia and infarction due to antihypertensive therapy

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    Eight cases of postural focal cerebral ischaemia due to antihypertensive medications presented to one neurologist over an eight-month period. Most patients were elderly and suffered from chronic hypertension; their symptoms resolved after the reduction or cessation of these medications. These findings re-emphasize that considerable caution is required when antihypertensive medications are used in elderly persons and in patients with chronic hypertension whose cerebral blood-flow autoregulatory curves are shifted to the right. We also draw attention to the fact that drug-induced hypotension may induce focal cerebral ischaemia rather than generalized cerebral ischaemia more frequently than is generally appreciated.

    Original languageEnglish
    Pages (from-to)412-4
    Number of pages3
    JournalThe Medical journal of Australia
    Issue number8
    Publication statusPublished - 20 Apr 1987


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