fMRI findings in an aphasic patient with reversed cerebral dominance for language

Everhard J. M. Vandervliet, Jo Verhoeven, Sebastiaan Engelborghs, Peter Paul De Deyn, Paul M. Parizel, Peter Marien

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7 Citations (Scopus)

Abstract

An 80-year-old right-handed woman with no history of brain damage or familial strain of left-handedness acutely developed aphasia associated with a left hemiparesis following a right hemisphere stroke. Brain MRI showed a posterior insular ischemic infarction extending to the temporo-parietal region of the right hemisphere. Severe overall language disruption (global aphasia) in the acute phase of the stroke rapidly evolved into conduction aphasia, characterized by a neurolinguistic profile of disproportionately severe repetition deficits and markedly distorted phonological skills. In the lesion phase of the stroke, a functional MRI study using a word repetition task was conducted which revealed a consistent pattern of right hemisphere activations. For the first time, right hemisphere language dominance is demonstrated by fMRI in a clear instance of crossed aphasia in a dextral.

Original languageEnglish
Pages (from-to)161-166
Number of pages6
JournalActa Neurologica Belgica
Volume108
Issue number4
Publication statusPublished - Dec 2008
Externally publishedYes

Cite this

Vandervliet, E. J. M., Verhoeven, J., Engelborghs, S., De Deyn, P. P., Parizel, P. M., & Marien, P. (2008). fMRI findings in an aphasic patient with reversed cerebral dominance for language. Acta Neurologica Belgica, 108(4), 161-166.