TY - JOUR
T1 - Fish oil and multivitamin supplementation reduces oxidative stress but not inflammation in healthy older adults: A randomised controlled trial
AU - Pipingas, A.
AU - Sinclair, A.
AU - Croft, Kevin
AU - Januszewski, A.S.
AU - Jenkins, A.J.
AU - Mori, Trevor
AU - Cockerell, R.
AU - Grima, N.A.
AU - Stough, C.
AU - Scholey, A.
AU - Myers, S.P.
AU - Sali, A.
AU - Pase, M.P.
PY - 2015
Y1 - 2015
N2 - © 2014 Elsevier Ltd. The effects of daily fish oil supplementation, with and without multivitamins, on biochemical markers of health were examined. Healthy adults (N = 160) were randomised to receive 3 g of salmon oil with a multivitamin, 6 g of salmon oil with a multivitamin, 6 g of salmon oil in isolation or placebo in a double-blind fashion on a daily basis for 16 weeks. Relative to placebo, both 6 g salmon oil groups displayed significantly lower F2-isoprostane levels at endpoint. Increases in red blood cell polyunsaturated fatty acids correlated with reductions in F2-isoprostanes. Treatment had no effect on inflammatory cytokines, C-reactive protein, fibrinogen, cholesterol or triacylglycerol.
AB - © 2014 Elsevier Ltd. The effects of daily fish oil supplementation, with and without multivitamins, on biochemical markers of health were examined. Healthy adults (N = 160) were randomised to receive 3 g of salmon oil with a multivitamin, 6 g of salmon oil with a multivitamin, 6 g of salmon oil in isolation or placebo in a double-blind fashion on a daily basis for 16 weeks. Relative to placebo, both 6 g salmon oil groups displayed significantly lower F2-isoprostane levels at endpoint. Increases in red blood cell polyunsaturated fatty acids correlated with reductions in F2-isoprostanes. Treatment had no effect on inflammatory cytokines, C-reactive protein, fibrinogen, cholesterol or triacylglycerol.
U2 - 10.1016/j.jff.2014.10.028
DO - 10.1016/j.jff.2014.10.028
M3 - Article
SN - 1756-4646
VL - 19
SP - 949
EP - 957
JO - Journal of Functional Foods
JF - Journal of Functional Foods
ER -