First-line antiretroviral treatment failure and associated factors in HIV patients at University of Gondar Teaching Hospital, Gondar, Northwest Ethiopia

Mohammed Biset Ayalew, Dawit Kumilachew Yimenu, Assefa Belay, Samson Getu, Derso Teju, Desalegn Endale, Yemisirach Tsegaye, Zebiba Wale

Research output: Contribution to journalArticlepeer-review

43 Citations (Scopus)

Abstract

Background: Antiretroviral therapy (ART) restores immune function and reduces HIV-related adverse outcomes. But treatment failure erodes this advantage and leads to an increased morbidity and compromised quality of life in HIV patients. The aim of this study was to determine the prevalence and factors associated with first-line ART failure in HIV patients at the University of Gondar Teaching Hospital. Patients and methods: A retrospective study was conducted on 340 adults who had started ART during the period of September 2011 to May 2015. Data regarding patients’ sociodemographics, baseline characteristics, and treatment-related information were collected through review of their medical charts. Data were analyzed using SPSS version 21. Descriptive statistics, cross-tabs, and binary and multiple logistic regressions were utilized. P
Original languageEnglish
Pages (from-to)141-146
Number of pages6
JournalHIV/AIDS: Research and Palliative Care
Volume8
DOIs
Publication statusPublished - 2 Sept 2016
Externally publishedYes

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