TY - JOUR
T1 - First-line antiretroviral treatment failure and associated factors in HIV patients at University of Gondar Teaching Hospital, Gondar, Northwest Ethiopia
AU - Ayalew, Mohammed Biset
AU - Yimenu, Dawit Kumilachew
AU - Belay, Assefa
AU - Getu, Samson
AU - Teju, Derso
AU - Endale, Desalegn
AU - Tsegaye, Yemisirach
AU - Wale, Zebiba
PY - 2016/9/2
Y1 - 2016/9/2
N2 - Background: Antiretroviral therapy (ART) restores immune function and reduces HIV-related adverse outcomes. But treatment failure erodes this advantage and leads to an increased morbidity and compromised quality of life in HIV patients. The aim of this study was to determine the prevalence and factors associated with first-line ART failure in HIV patients at the University of Gondar Teaching Hospital. Patients and methods: A retrospective study was conducted on 340 adults who had started ART during the period of September 2011 to May 2015. Data regarding patients’ sociodemographics, baseline characteristics, and treatment-related information were collected through review of their medical charts. Data were analyzed using SPSS version 21. Descriptive statistics, cross-tabs, and binary and multiple logistic regressions were utilized. P
AB - Background: Antiretroviral therapy (ART) restores immune function and reduces HIV-related adverse outcomes. But treatment failure erodes this advantage and leads to an increased morbidity and compromised quality of life in HIV patients. The aim of this study was to determine the prevalence and factors associated with first-line ART failure in HIV patients at the University of Gondar Teaching Hospital. Patients and methods: A retrospective study was conducted on 340 adults who had started ART during the period of September 2011 to May 2015. Data regarding patients’ sociodemographics, baseline characteristics, and treatment-related information were collected through review of their medical charts. Data were analyzed using SPSS version 21. Descriptive statistics, cross-tabs, and binary and multiple logistic regressions were utilized. P
UR - http://www.scopus.com/inward/record.url?scp=84987942365&partnerID=8YFLogxK
U2 - 10.2147/hiv.s112048
DO - 10.2147/hiv.s112048
M3 - Article
SN - 1179-1373
VL - 8
SP - 141
EP - 146
JO - HIV/AIDS: Research and Palliative Care
JF - HIV/AIDS: Research and Palliative Care
ER -