Fetal growth restriction and asthma: Is the damage done?

Kimberley C W Wang; Alan L James; Peter B Noble

doi:10.1152/physiol.00042.2020

Fetal growth restriction and asthma: Is the damage done?

Research output: Contribution to journal › Review article › peer-review

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Abstract

Trajectories of airway remodeling and functional impairment in asthma are consistent with the notion that airway pathology precedes or coincides with the onset of asthma symptoms and may be present at birth. An association between intrauterine growth restriction (IUGR) and asthma development has also been established, and there is value in understanding the underlying mechanism. This review considers airway pathophysiology as a consequence of IUGR that increases susceptibility to asthma.

Original language	English
Pages (from-to)	256-266
Number of pages	11
Journal	Physiology
Volume	36
Issue number	4
DOIs	https://doi.org/10.1152/physiol.00042.2020
Publication status	Published - 1 Jul 2021

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1152/physiol.00042.2020

Wang et al., 2021 Fetal growth restriction and asthmaAccepted author manuscript, 195 KB

Fetal growth restriction, low birth weight and the development of asthma
Wang, K. (Investigator 01)
NHMRC National Health and Medical Research Council
1/01/17 → 31/12/22
Project: Research
Role of airway smooth muscle on the development of asthma
Wang, K. (Investigator 01)
NHMRC National Health and Medical Research Council
1/01/15 → 31/12/19
Project: Research

Cite this

@article{e011e85ea24d41c6ab6d04f23e715266,

title = "Fetal growth restriction and asthma: Is the damage done?",

abstract = "Trajectories of airway remodeling and functional impairment in asthma are consistent with the notion that airway pathology precedes or coincides with the onset of asthma symptoms and may be present at birth. An association between intrauterine growth restriction (IUGR) and asthma development has also been established, and there is value in understanding the underlying mechanism. This review considers airway pathophysiology as a consequence of IUGR that increases susceptibility to asthma.",

author = "Wang, \{Kimberley C W\} and James, \{Alan L\} and Noble, \{Peter B\}",

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pages = "256--266",

journal = "Physiology",

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publisher = "American Physiological Society",

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T1 - Fetal growth restriction and asthma

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AU - Wang, Kimberley C W

AU - James, Alan L

AU - Noble, Peter B

PY - 2021/7/1

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N2 - Trajectories of airway remodeling and functional impairment in asthma are consistent with the notion that airway pathology precedes or coincides with the onset of asthma symptoms and may be present at birth. An association between intrauterine growth restriction (IUGR) and asthma development has also been established, and there is value in understanding the underlying mechanism. This review considers airway pathophysiology as a consequence of IUGR that increases susceptibility to asthma.

AB - Trajectories of airway remodeling and functional impairment in asthma are consistent with the notion that airway pathology precedes or coincides with the onset of asthma symptoms and may be present at birth. An association between intrauterine growth restriction (IUGR) and asthma development has also been established, and there is value in understanding the underlying mechanism. This review considers airway pathophysiology as a consequence of IUGR that increases susceptibility to asthma.

U2 - 10.1152/physiol.00042.2020

DO - 10.1152/physiol.00042.2020

M3 - Review article

C2 - 34159809

SN - 1548-9221

VL - 36

SP - 256

EP - 266

JO - Physiology

JF - Physiology

IS - 4

ER -

Fetal growth restriction and asthma: Is the damage done?

Abstract

UN SDGs

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Projects

Fetal growth restriction, low birth weight and the development of asthma

Role of airway smooth muscle on the development of asthma

Cite this