Ferrocenyl-Based P,N Catalysts for the Mono-alpha-Arylation of Acetone

Christian Gaebler; Marcus Korb; Dieter Schaarschmidt; Alexander Hildebrandt; Heinrich Lang

doi:10.1002/adsc.201400235

Ferrocenyl-Based P,N Catalysts for the Mono-alpha-Arylation of Acetone

Christian Gaebler, Marcus Korb, Dieter Schaarschmidt, Alexander Hildebrandt, Heinrich Lang

Research output: Contribution to journal › Article › peer-review

20 Citations (Web of Science)

Abstract

The novel air-stable diferrocenyl-based P,N ligands PFc(2)(C6H4-2-NMe2) (1) and PFc2(C6H4-2-piperidyl) (2) [Fc = Fe(eta(5)-C5H4)(eta(5)-C5H5)] for the highly effective palladium-catalyzed mono-alpha-arylation of acetone are reported. High yields could be obtained for the C-C coupling of several chloro- and bromoarenes at palladium loadings as low as 0.5 mol% of [Pd(cinnamyl) Cl](2).

Original language	English
Pages (from-to)	2979-2983
Number of pages	5
Journal	ADVANCED SYNTHESIS & CATALYSIS
Volume	356
Issue number	14-15
DOIs	https://doi.org/10.1002/adsc.201400235
Publication status	Published - 13 Oct 2014
Externally published	Yes

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title = "Ferrocenyl-Based P,N Catalysts for the Mono-alpha-Arylation of Acetone",

abstract = "The novel air-stable diferrocenyl-based P,N ligands PFc(2)(C6H4-2-NMe2) (1) and PFc2(C6H4-2-piperidyl) (2) [Fc = Fe(eta(5)-C5H4)(eta(5)-C5H5)] for the highly effective palladium-catalyzed mono-alpha-arylation of acetone are reported. High yields could be obtained for the C-C coupling of several chloro- and bromoarenes at palladium loadings as low as 0.5 mol% of [Pd(cinnamyl) Cl](2).",

keywords = "acetone, ferrocenylphosphanes, monoarylation, palladium, phosphanes, CROSS-COUPLING REACTIONS, KETONES, MONOARYLATION, LIGANDS, HECK",

author = "Christian Gaebler and Marcus Korb and Dieter Schaarschmidt and Alexander Hildebrandt and Heinrich Lang",

year = "2014",

month = oct,

day = "13",

doi = "10.1002/adsc.201400235",

language = "English",

volume = "356",

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number = "14-15",

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TY - JOUR

T1 - Ferrocenyl-Based P,N Catalysts for the Mono-alpha-Arylation of Acetone

AU - Gaebler, Christian

AU - Korb, Marcus

AU - Schaarschmidt, Dieter

AU - Hildebrandt, Alexander

AU - Lang, Heinrich

PY - 2014/10/13

Y1 - 2014/10/13

N2 - The novel air-stable diferrocenyl-based P,N ligands PFc(2)(C6H4-2-NMe2) (1) and PFc2(C6H4-2-piperidyl) (2) [Fc = Fe(eta(5)-C5H4)(eta(5)-C5H5)] for the highly effective palladium-catalyzed mono-alpha-arylation of acetone are reported. High yields could be obtained for the C-C coupling of several chloro- and bromoarenes at palladium loadings as low as 0.5 mol% of [Pd(cinnamyl) Cl](2).

AB - The novel air-stable diferrocenyl-based P,N ligands PFc(2)(C6H4-2-NMe2) (1) and PFc2(C6H4-2-piperidyl) (2) [Fc = Fe(eta(5)-C5H4)(eta(5)-C5H5)] for the highly effective palladium-catalyzed mono-alpha-arylation of acetone are reported. High yields could be obtained for the C-C coupling of several chloro- and bromoarenes at palladium loadings as low as 0.5 mol% of [Pd(cinnamyl) Cl](2).

KW - acetone

KW - ferrocenylphosphanes

KW - monoarylation

KW - palladium

KW - phosphanes

KW - CROSS-COUPLING REACTIONS

KW - KETONES

KW - MONOARYLATION

KW - LIGANDS

KW - HECK

U2 - 10.1002/adsc.201400235

DO - 10.1002/adsc.201400235

M3 - Article

SN - 1615-4150

VL - 356

SP - 2979

EP - 2983

JO - ADVANCED SYNTHESIS & CATALYSIS

JF - ADVANCED SYNTHESIS & CATALYSIS

IS - 14-15

ER -

Ferrocenyl-Based P,N Catalysts for the Mono-alpha-Arylation of Acetone

Abstract

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