Feasibility of real-time polymerase chain reaction in whole blood to identify Streptococcus pneumonia in patients with community-acquired pneumonia

C.W.H. Kee, S. Palladino, I. Kay, T.M. Pryce, R. Murray, J. Rello, M. Gallego, M. Lujan, C Munoz-Almagro, Grant Waterer

Research output: Contribution to journalArticlepeer-review

30 Citations (Scopus)

Abstract

We assessed a real-time quantitative polymerase chain reaction (PCR) assay targeting the lytA and ply gene of Streptococcus pneumoniae. Both assays were applied to whole blood samples from 28 adult patients with community-acquired pneumonia. Our findings suggest thelytA PCR is more sensitive, and the quantitative aspect of the assay shows promise as an aid to clinical judgment.
Original languageEnglish
Pages (from-to)72-75
JournalDiagnostic Microbiology and Infectious Disease
Volume61
Issue number1
DOIs
Publication statusPublished - 2008

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