FANTOM4 EdgeExpressDB: An integrated database of promoters, genes, microRNAs, expression dynamics and regulatory interactions

Jessica Severin, Andrew M. Waterhouse, Hideya Kawaji, Timo Lassmann, Erik Van Nimwegen, Piotr J. Balwierz, Michiel J L De Hoon, David A. Hume, Piero Carninci, Yoshihide Hayashizaki, Harukazu Suzuki, Carsten O. Daub, Alistair R.R. Forrest

Research output: Contribution to journalArticle

50 Citations (Scopus)

Abstract

EdgeExpressDB is a novel database and set of interfaces for interpreting biological networks and comparing large high-throughput expression datasets that requires minimal development for new data types and search patterns. The FANTOM4 EdgeExpress database http://fantom.gsc.riken.jp/4/ edgeexpress summarizes gene expression patterns in the context of alternative promoter structures and regulatory transcription factors and microRNAs using intuitive gene-centric and sub-network views. This is an important resource for gene regulation in acute myeloid leukemia, monocyte/macrophage differentiation and human transcriptional networks.

Original languageEnglish
Article numberR39
JournalGenome Biology
Volume10
Issue number4
DOIs
Publication statusPublished - 19 Apr 2009
Externally publishedYes

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