@article{3bec75c427db49eeb52a8868261e7f51,
title = "Family-Based Approaches to Cardiovascular Health Promotion",
abstract = "Cardiovascular disease is the leading cause of mortality in the world, and the increasing burden is largely a consequence of modifiable behavioral risk factors that interact with genomics and the environment. Continuous cardiovascular health promotion and disease prevention throughout the lifespan is critical, and the family is a central entity in this process. In this review, we describe the potential rationale and mechanisms that contribute to the importance of family for cardiovascular health promotion, focusing on: 1) mutual interdependence of the family system; 2) shared environment; 3) parenting style; 4) caregiver perceptions; and 5) genomics. We conclude that family-based approaches that target both caregivers and children, encourage communication among the family unit, and address the structural and environmental conditions in which families live and operate are likely to be the most effective approach to promote cardiovascular health. We describe lessons learned, future implications, and applications to ongoing and planned studies.",
keywords = "cardiovascular disease, children, genomics",
author = "Rajesh Vedanthan and Sameer Bansilal and Soto, {Ana Victoria} and Kovacic, {Jason C.} and Jacqueline Latina and Risa Jaslow and Maribel Santana and Elio Gorga and Andrew Kasarskis and Roger Hajjar and Schadt, {Eric E.} and Bj{\"o}rkegren, {Johan L.} and Fayad, {Zahi A.} and Valentin Fuster",
note = "Funding Information: Dr. Vedanthan is supported by the Fogarty International Center of the National Institutes of Health (K01TW009218). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health or the American Heart Association. Drs. Kovacic and Bj{\"o}rkegren are supported by the National Heart, Lung, and Blood Institute (K08HL111330 and R01HL125863, respectively), Foundation Leducq Transatlantic Network of Excellence Awards, and AstraZeneca. Dr. Fuster is supported by the National Heart, Lung, and Blood Institute (5U01HL114200). Drs. Vedanthan, Bansilal, Soto, Kovacic, Latina, Kasarskis, Hajjar, Schadt, Bj{\"o}rkegren, Fayad, and Fuster, Ms. Jaslow, and Ms. Santana are supported by the American Heart Association (14SFRN20490315). Dr. Gorga has reported that he has no relationships relevant to the contents of this paper to disclose. Deepak Bhatt, MD, served as Guest Editor for this paper. Publisher Copyright: {\textcopyright} 2016 American College of Cardiology Foundation.",
year = "2016",
month = apr,
day = "12",
doi = "10.1016/j.jacc.2016.01.036",
language = "English",
volume = "67",
pages = "1725--1737",
journal = "Journal of the American College of Cardiology",
issn = "0735-1097",
publisher = "Academic Press",
number = "14",
}