Factors Associated with Time to Full Feeds in Preterm Very Low Birth Weight Infants

Gaurav Patwardhan; Ankit Soni; Nitin Rachwani; Sandeep Kadam; Sanjay Patole; Anand Pandit

doi:10.1093/tropej/fmx102

Factors Associated with Time to Full Feeds in Preterm Very Low Birth Weight Infants

Gaurav Patwardhan, Ankit Soni, Nitin Rachwani, Sandeep Kadam, Sanjay Patole, Anand Pandit

UWA Medical School

Research output: Contribution to journal › Article › peer-review

18 Citations (Scopus)

Abstract

Background: Feeding intolerance prolongs time to full feeds (TFFs) in preterm infants. We studied factors associated with TFF in preterm infants on standardized feeding regimen (SFR) and routine probiotic supplementation (RPS).

Methods: This is a prospective cohort study of preterm infants

Results: In total, 37 of 304 admitted infants died before reaching full feeds. Median (interquartile range) gestation, birth weight and TFF were 31.4 (30-33.05) weeks, 1210 (1066-1400) g and 11 (8-15) days, respectively. Gestation and birthweight were inversely correlated with TFF, whereas low Apgar's, sepsis, patent ductus arteriosus (PDA) and respiratory distress syndrome were directly correlated with TFF. Growth-restricted infants had significantly shorter TFF vs. appropriate for gestational age infants, probably because of higher gestation. On multivariate analysis gestation, sepsis and PDA were significant predictors of TFF.

Conclusion: In preterm infants managed with SFR and RPS, gestation had inverse correlation with TFF, whereas sepsis and PDA had direct correlation with TFF.

Original language	English
Pages (from-to)	495-500
Number of pages	6
Journal	Journal of Tropical Pediatrics
Volume	64
Issue number	6
DOIs	https://doi.org/10.1093/tropej/fmx102
Publication status	Published - Dec 2018

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title = "Factors Associated with Time to Full Feeds in Preterm Very Low Birth Weight Infants",

abstract = "Background: Feeding intolerance prolongs time to full feeds (TFFs) in preterm infants. We studied factors associated with TFF in preterm infants on standardized feeding regimen (SFR) and routine probiotic supplementation (RPS).Methods: This is a prospective cohort study of preterm infantsResults: In total, 37 of 304 admitted infants died before reaching full feeds. Median (interquartile range) gestation, birth weight and TFF were 31.4 (30-33.05) weeks, 1210 (1066-1400) g and 11 (8-15) days, respectively. Gestation and birthweight were inversely correlated with TFF, whereas low Apgar's, sepsis, patent ductus arteriosus (PDA) and respiratory distress syndrome were directly correlated with TFF. Growth-restricted infants had significantly shorter TFF vs. appropriate for gestational age infants, probably because of higher gestation. On multivariate analysis gestation, sepsis and PDA were significant predictors of TFF.Conclusion: In preterm infants managed with SFR and RPS, gestation had inverse correlation with TFF, whereas sepsis and PDA had direct correlation with TFF.",

keywords = "time to full feeds, feed intolerance, preterm, risk factors, small for gestation, PATENT DUCTUS-ARTERIOSUS, NECROTIZING ENTEROCOLITIS, TOLERANCE, NUTRITION",

author = "Gaurav Patwardhan and Ankit Soni and Nitin Rachwani and Sandeep Kadam and Sanjay Patole and Anand Pandit",

year = "2018",

month = dec,

doi = "10.1093/tropej/fmx102",

language = "English",

volume = "64",

pages = "495--500",

journal = "Journal of Tropical Pediatrics",

issn = "0142-6338",

publisher = "Oxford University Press",

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TY - JOUR

T1 - Factors Associated with Time to Full Feeds in Preterm Very Low Birth Weight Infants

AU - Patwardhan, Gaurav

AU - Soni, Ankit

AU - Rachwani, Nitin

AU - Kadam, Sandeep

AU - Patole, Sanjay

AU - Pandit, Anand

PY - 2018/12

Y1 - 2018/12

N2 - Background: Feeding intolerance prolongs time to full feeds (TFFs) in preterm infants. We studied factors associated with TFF in preterm infants on standardized feeding regimen (SFR) and routine probiotic supplementation (RPS).Methods: This is a prospective cohort study of preterm infantsResults: In total, 37 of 304 admitted infants died before reaching full feeds. Median (interquartile range) gestation, birth weight and TFF were 31.4 (30-33.05) weeks, 1210 (1066-1400) g and 11 (8-15) days, respectively. Gestation and birthweight were inversely correlated with TFF, whereas low Apgar's, sepsis, patent ductus arteriosus (PDA) and respiratory distress syndrome were directly correlated with TFF. Growth-restricted infants had significantly shorter TFF vs. appropriate for gestational age infants, probably because of higher gestation. On multivariate analysis gestation, sepsis and PDA were significant predictors of TFF.Conclusion: In preterm infants managed with SFR and RPS, gestation had inverse correlation with TFF, whereas sepsis and PDA had direct correlation with TFF.

AB - Background: Feeding intolerance prolongs time to full feeds (TFFs) in preterm infants. We studied factors associated with TFF in preterm infants on standardized feeding regimen (SFR) and routine probiotic supplementation (RPS).Methods: This is a prospective cohort study of preterm infantsResults: In total, 37 of 304 admitted infants died before reaching full feeds. Median (interquartile range) gestation, birth weight and TFF were 31.4 (30-33.05) weeks, 1210 (1066-1400) g and 11 (8-15) days, respectively. Gestation and birthweight were inversely correlated with TFF, whereas low Apgar's, sepsis, patent ductus arteriosus (PDA) and respiratory distress syndrome were directly correlated with TFF. Growth-restricted infants had significantly shorter TFF vs. appropriate for gestational age infants, probably because of higher gestation. On multivariate analysis gestation, sepsis and PDA were significant predictors of TFF.Conclusion: In preterm infants managed with SFR and RPS, gestation had inverse correlation with TFF, whereas sepsis and PDA had direct correlation with TFF.

KW - time to full feeds

KW - feed intolerance

KW - preterm

KW - risk factors

KW - small for gestation

KW - PATENT DUCTUS-ARTERIOSUS

KW - NECROTIZING ENTEROCOLITIS

KW - TOLERANCE

KW - NUTRITION

U2 - 10.1093/tropej/fmx102

DO - 10.1093/tropej/fmx102

M3 - Article

SN - 0142-6338

VL - 64

SP - 495

EP - 500

JO - Journal of Tropical Pediatrics

JF - Journal of Tropical Pediatrics

IS - 6

ER -

Factors Associated with Time to Full Feeds in Preterm Very Low Birth Weight Infants

Abstract

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