@article{753dd247d4494c8ebef622bc949c9a5d,
title = "Facial Function in Bell Palsy in a Cohort of Children Randomized to Prednisolone or Placebo 12 Months After Diagnosis",
abstract = "Background: Information on the medium-term recovery of children with Bell palsy or acute idiopathic lower motor neuron facial paralysis is limited. Methods: We followed up children aged 6 months to <18 years with Bell palsy for 12 months after completion of a randomized trial on the use of prednisolone. We assessed facial function using the clinician-administered House-Brackmann scale and the modified parent-administered House-Brackmann scale. Results: One hundred eighty-seven children were randomized to prednisolone (n = 93) or placebo (n = 94). At six months, the proportion of patients who had recovered facial function based on the clinician-administered House-Brackmann scale was 98% (n = 78 of 80) in the prednisolone group and 93% (n = 76 of 82) in the placebo group. The proportion of patients who had recovered facial function based on the modified parent-administered House-Brackmann scale was 94% (n = 75 of 80) vs 89% (n = 72 of 81) at six months (OR 1.88; 95% CI 0.60, 5.86) and 96% (n = 75 of 78) vs 92% (n = 73 of 79) at 12 months (OR 3.12; 95% CI 0.61, 15.98). Conclusions: Although the vast majority had complete recovery of facial function at six months, there were some children without full recovery of facial function at 12 months, regardless of prednisolone use.",
keywords = "Clinical neurology, Emergency medicine, Facial function, Pediatrics",
author = "Babl, {Franz E.} and David Herd and Borland, {Meredith L.} and Amit Kochar and Ben Lawton and Jason Hort and Adam West and Shane George and Ed Oakley and Wilson, {Catherine L.} and Hopper, {Sandy M.} and Cheek, {John A.} and Stephen Hearps and Mackay, {Mark T.} and Dalziel, {Stuart R.} and Lee, {Katherine J.}",
note = "Funding Information: Funding: The study was funded by a grant from the National Health and Medical Research Council (NHMRC, project grant GNT1078069 ), Canberra, Australia; the Emergency Medicine Foundation ( EMSS-312R26-2016-GEORGE ), Brisbane, Australia; and the Perth Children's Hospital Foundation project grant #9670 , Perth, Australia. The PREDICT research network was part funded by an NHMRC Center of Research Excellence grant ( GNT1058560 ), Canberra, Australia; the Murdoch Children's Research Institute, Melbourne, Australia; and the Victorian Government's Operational Infrastructure Support program . F.E.B.'s time was part funded by a grant from the Royal Children's Hospital Foundation , Melbourne, Victoria, Australia, and an NHMRC Investigator Leadership grant. S.R.D.'s time was part funded by the Health Research Council of New Zealand ( HRC13/556 ) and Cure Kids , Auckland, New Zealand. Publisher Copyright: {\textcopyright} 2024 Elsevier Inc.",
year = "2024",
month = apr,
doi = "10.1016/j.pediatrneurol.2024.01.011",
language = "English",
volume = "153",
pages = "44--47",
journal = "Pediatric Neurology",
issn = "0887-8994",
publisher = "Elsevier",
}