Abstract
We propose a method to image cutaneous lymphatic vessels in vivo with optical coherence tomography (OCT). Our method segments the transparent lymphatic vessels by thresholding the OCT signal after calibration for systematic variations due to the confocal effect and the sensitivity drop-off, and subsequent compensation for light attenuation with depth. We describe the method and present a pilot demonstration on two human burn scar patients undergoing ablative laser fractionation treatment. The results show visualization of the lymphatic vessels (diameter: ∼30-150 μm) separate from the blood microvasculature network.
| Original language | English |
|---|---|
| Title of host publication | 2016 IEEE Photonics Conference, IPC 2016 |
| Place of Publication | USA |
| Publisher | IEEE, Institute of Electrical and Electronics Engineers |
| Pages | 138-139 |
| Number of pages | 2 |
| ISBN (Electronic) | 9781509019069 |
| DOIs | |
| Publication status | Published - 23 Jan 2017 |
| Event | 29th IEEE Photonics Conference, IPC 2016 - Waikoloa, United States Duration: 2 Oct 2016 → 6 Oct 2016 |
Conference
| Conference | 29th IEEE Photonics Conference, IPC 2016 |
|---|---|
| Country | United States |
| City | Waikoloa |
| Period | 2/10/16 → 6/10/16 |
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Extracting something from nothing : In vivo imaging of human cutaneous lymphatic vessels using optical coherence tomography. / Gong, Peijun; Es'Haghian, Shaghayegh; Harms, Karl Anton; Murray, Alexandra; Rea, Suzanne; Wood, Fiona M.; Sampson, David D.; McLaughlin, Robert A.
2016 IEEE Photonics Conference, IPC 2016. USA : IEEE, Institute of Electrical and Electronics Engineers, 2017. p. 138-139 7831014.Research output: Chapter in Book/Conference paper › Conference paper
TY - GEN
T1 - Extracting something from nothing
T2 - In vivo imaging of human cutaneous lymphatic vessels using optical coherence tomography
AU - Gong, Peijun
AU - Es'Haghian, Shaghayegh
AU - Harms, Karl Anton
AU - Murray, Alexandra
AU - Rea, Suzanne
AU - Wood, Fiona M.
AU - Sampson, David D.
AU - McLaughlin, Robert A.
PY - 2017/1/23
Y1 - 2017/1/23
N2 - We propose a method to image cutaneous lymphatic vessels in vivo with optical coherence tomography (OCT). Our method segments the transparent lymphatic vessels by thresholding the OCT signal after calibration for systematic variations due to the confocal effect and the sensitivity drop-off, and subsequent compensation for light attenuation with depth. We describe the method and present a pilot demonstration on two human burn scar patients undergoing ablative laser fractionation treatment. The results show visualization of the lymphatic vessels (diameter: ∼30-150 μm) separate from the blood microvasculature network.
AB - We propose a method to image cutaneous lymphatic vessels in vivo with optical coherence tomography (OCT). Our method segments the transparent lymphatic vessels by thresholding the OCT signal after calibration for systematic variations due to the confocal effect and the sensitivity drop-off, and subsequent compensation for light attenuation with depth. We describe the method and present a pilot demonstration on two human burn scar patients undergoing ablative laser fractionation treatment. The results show visualization of the lymphatic vessels (diameter: ∼30-150 μm) separate from the blood microvasculature network.
KW - attenuation coefficient
KW - blood vessel
KW - burn scars
KW - lymphatic vessel
KW - Optical coherence tomography (OCT)
KW - speckle decorrelation
UR - http://www.scopus.com/inward/record.url?scp=85014222030&partnerID=8YFLogxK
U2 - 10.1109/IPCon.2016.7831014
DO - 10.1109/IPCon.2016.7831014
M3 - Conference paper
SP - 138
EP - 139
BT - 2016 IEEE Photonics Conference, IPC 2016
PB - IEEE, Institute of Electrical and Electronics Engineers
CY - USA
ER -