Abstract
Extracellular vesicles (EVs) are small cell vesicles that are derived from the cell membrane in response to different biological processes. There is growing evidence supporting the association between EVs and cardiovascular disease. In this project, we standardized and validated a method to evaluate EVs using the AttuneTM Nxt Acoustic Focusing Flow Cytometer system (ThermoFisherScientific) and evaluate the EVs performance across the blood pressure spectrum. We found a relationship between EVs and high-risk phenotypes (night-time BP, organ damage, and cardiovascular risk) which demonstrate their contribution to EVs biogenesis.
| Original language | English |
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| Qualification | Doctor of Philosophy |
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| Award date | 9 Aug 2023 |
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| Publication status | Unpublished - 2022 |
Access to Document
- THESIS - DOCTOR OF PHILOSOPHY - LUGO GAVIDIA Leslie Marisol - 2022_
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